Int J Gynecol Cancer
April 2023
Objective: To evaluate the non-inferiority and safety of simple hysterectomy in early stage (<2 cm) cervical cancer.
Methods: This proof-of-concept randomized phase II non-inferiority trial was performed between May 2015 and April 2018 in three oncological centers in Northeast Brazil. Patients with International Federation of Gynecology and Obstetrics (FIGO) 2009 stages IA2-IB1 cervical cancer and tumors ≤2 cm were treated with either simple or modified radical hysterectomy (Querleu-Morrow type B2).
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