Effect of chronic cabergoline treatment and testosterone replacement on metabolism in male patients with prolactinomas.

Introduction: Hyperprolactinemia and hypogonadism are reportedly associated with an impaired metabolic profile. The current study aimed at investigating the effects of testosterone replacement and cabergoline (CAB) treatment on the metabolic profile in male hyperprolactinemic patients.

Patients And Methods: Thirty-two men with prolactinomas, including 22 with total testosterone (TT) <8 nmol/l (HG, 69%) and 10 with TT >8 nmol/l (non-HG, 31%), were entered in the study.

Effect of cabergoline on metabolism in prolactinomas.

Introduction: Hyperprolactinemia has been implicated in the pathogenesis of obesity and glucose intolerance and is reportedly associated with an impaired metabolic profile. The current study aimed at investigating the effects of 12- and 60-month treatment with cabergoline (CAB) on metabolic syndrome (MetS) in patients with prolactinomas.

Patients And Methods: 61 patients with prolactinomas (13 men, 48 women, 41 with microadenoma, 20 with macroadenoma), aged 34.

An easy schedule for postsurgical radioiodine administration in newly diagnosed differentiated thyroid carcinoma patients.

Objective: To validate the simplest approach to preparing patients with differentiated thyroid carcinoma (DTC) for (131) I-administration ((131) I-A), minimizing the impact of hypothyroidism.

Design: Panel study.

Patients: Ninety patients with DTC were enrolled in the study.

Teriparatide vs. alendronate as a treatment for osteoporosis: changes in biochemical markers of bone turnover, BMD and quality of life.

Background: We studied the use of teriparatide in postmenopausal women with severe osteoporosis.

Material/methods: Two groups (A and B) of patients affected by severe osteoporosis (T-score ≤-2.5 at bone mineral density were analyzed and 2 vertebral fractures on radiograph).

Stricter criteria increase the validity of a quick intraoperative parathyroid hormone assay in primary hyperparathyroidism.

Background: A "quick" intraoperative parathyroid hormone (PTH) (QPTH) assay evaluates parathyroid hypersecretion during parathyroidectomy. We investigated the likelihood of increasing surgical success rates by introducing stricter parameters in intraoperative PTH monitoring.

Material/methods: One hundred one patients with sporadic primary hyperparathyroidism were studied.