Human N-acetyltransferase 2 () gene variability in Brazilian populations from different geographical areas.

Several polymorphisms altering the activity have already been identified. The geographical distribution of variants has been extensively studied and has been demonstrated to vary significantly among different ethnic population. Here, we describe the genetic variability of human N-acetyltransferase 2 () gene and the predominant genotype-deduced acetylation profiles of Brazilians.

Migration among individuals with leprosy: a population-based study in central Brazil.

This study investigates social and clinical factors associated with migration among individuals affected by leprosy. A cross-sectional study was conducted among those newly diagnosed with leprosy (2006-2008), in 79 endemic municipalities in the state of Tocantins, Brazil (N = 1,074). In total, 76.

Motives and determinants for residence change after leprosy diagnosis, central Brazil.

Objective: To determine the extent of population movement after diagnosis with leprosy and to describe the underlying motives and determinants for relocation.

Design: A cross-sectional study was conducted among those newly diagnosed with leprosy in 79 endemic municipalities in the state of Tocantins, central Brazil. Individuals were identified through the National Information System for Notifiable Diseases (SINAN) database and interviewed with structured questionnaires.