Prevalence of human papillomavirus types 6, 11, 16 and 18 in young Austrian women - baseline data of a phase III vaccine trial.

Introduction: Cervical cancer is the second most common cancer among women worldwide. In the absence of changing risk or intervention, it is projected that in comparison with 2002 there will be a 40% increase in the number of new cases of cervical cancer by 2020. HPV types 16 and 18 cause 70% of cervical cancers worldwide, 50% of high-grade cervical intraepithelial neoplasias and 25% of low-grade neoplasias.

Anaesthesia for brachytherapy.

Purpose Of Review: The demand for anaesthesia in brachytherapy is increasing. Patients often present with high-risk factors and multiple comorbidities. To achieve a stable position of the implants, immobility is often mandatory.

Inguinal sentinel lymph node dissection vs. complete inguinal lymph node dissection in patients with vulvar cancer.

Background: The aim of this retrospective study was to ascertain the postoperative morbidity in patients with vulvar cancer undergoing sentinel lymph node vs. complete inguinal lymph node dissection.

Patients And Methods: In total 29 and 46 patients with vulvar cancer, were treated by the technique of inguinal sentinel lymph node dissection or complete inguinal lymph node dissection, respectively.

C-reactive protein serum levels are closely associated with lymph node status, but not with prognosis in patients with vulvar cancer.

Objective: To evaluate whether C-reactive protein (CRP) serum levels can be used as prognostic parameter in patients with vulvar cancer.

Study Design: CRP serum levels were measured at the time of first diagnosis of squamous cell vulvar cancer. Sixty-seven patients were enrolled; results were correlated to clinical data.

Groin metastasis after extensive microinvasive vulvar cancer. A case report.

Background: An increasing incidence of vulvar intraepithelial neoplasia and microinvasive vulvar cancer is being observed in younger patients. The treatment of choice is wide local excision.

Case: A 53-year-old woman had HPV-related disease for more than 20 years.

A polymorphism in the matrix metalloproteinase-1 gene promoter is associated with the prognosis of patients with ovarian cancer.

Objective: The enzyme matrix metalloproteinase (MMP)-1 is involved in ovarian carcinogenesis. A common guanine insertion-deletion promoter polymorphism within the gene encoding MMP-1 (MMP1) has been suggested to be a candidate gene for ovarian cancer. We investigated whether this common polymorphism can also serve as independent prognostic parameter in a large series of affected women.

A common interleukin-6 promoter polymorphism in patients with vulvar cancer.

Objective: Besides its important role in immune response and inflammatory processes the cytokine interleukin-6 (IL-6) is crucially involved in carcinogenesis. A common polymorphism within the gene encoding IL-6 (IL6) is known to alter IL-6 protein expression and has been associated with patients' prognosis in various malignancies. No data are available with respect to vulvar cancer.