Publications by authors named "Lucia Miguel Escuder"
Article Synopsis
- Ocular toxoplasmosis (OT), caused by the Toxoplasma gondii parasite, is the leading cause of posterior uveitis globally, which can lead to visual impairment and blindness.
- A systematic review and meta-analysis of 72 studies identified various factors influencing recurrences and visual impairment in OT patients, focusing on clinical, environmental, parasite, host, and treatment-related factors.
- The analysis included 4,200 patients, revealing a recurrence rate of 49%, notably higher in South America compared to Europe.
Cystoid macular edema (CME) is the most common cause of decreased visual acuity after both vitrectomy and cataract surgery. Various strategies have been used for its treatment, such as intravitreal corticosteroids. The intravitreal fluocinolone acetonide implant (Iluvien) is approved for the treatment of persisting diabetic macular edema and for the prevention of recurrence of non-infectious uveitis affecting the posterior segment.
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- Anti-TNF-α-induced lupus (ATIL) is a rare form of drug-induced lupus that can occur in patients undergoing anti-TNF-α therapy, particularly those with non-infectious uveitis (NIU).
- The study presents three cases of patients who developed symptoms like positive antinuclear antibodies (ANA), arthritis, and skin lesions after starting adalimumab, which resolved upon withdrawal of the medication.
- The findings suggest common characteristics among these cases, such as the onset of symptoms linked to anti-TNF-α treatment and a review of existing literature supports their classification within ATIL.
Article Synopsis
- - The study investigates clinical and epidemiological features of Vogt-Koyanagi-Harada (VKH) disease in Spain, analyzing data from 112 patients over a minimum of six months.
- - The majority of participants were women (83.9%) with an average age of 37.5 years; the disease was often classified as incomplete acute, with corticosteroids being the most common treatment.
- - Findings indicate that VKH patients generally experience good visual outcomes, though complications like cataracts and ocular hypertension are prevalent.
Adalimumab in Elderly Patients with Non-Infectious Uveitis. Safety and Efficacy.
Ocul Immunol Inflamm
November 2021
: To assess the efficacy and safety of adalimumab in elderly patients with noninfectious uveitis (NIU).: An observational, retrospective, multicenter study was done. Changes in best-corrected visual acuity (BCVA), inflammatory activity parameters, central retinal thickness (CRT), and the occurrence of adverse events (AE) developed during follow-up were recorded.
View Article and Find Full Text PDFWe investigate whether the clinical presentations and outcomes of Legionella pneumonia in human immunodeficiency virus (HIV)-infected patients were comparable to those seen in non-HIV-infected patients (case-control design). HIV-infected individuals presented neither a more severe disease nor a worse clinical outcome than matched HIV-negative control patients.
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