Publications by authors named "Lucia Maria Bruno"
Diagnostic accuracy of faecal calprotectin in a symptom-based algorithm for early diagnosis of inflammatory bowel disease adjusting for differential verification bias using a Bayesian approach.
Scand J Gastroenterol
October 2020
Article Synopsis
- A study aimed to improve early diagnosis of inflammatory bowel disease (IBD) in primary care by using faecal calprotectin (fCAL) tests integrated with specific diagnostic criteria.
- General practitioners (GPs) identified patients with major or minor alarm symptoms, leading to fCAL testing and follow-up.
- The results showed that fCAL testing had a sensitivity of 74.8% and a high negative predictive value of 96.2%, indicating it may help rule out IBD in symptomatic patients.
Subjects affected by thalassemia major (TM) often have reduced bone mass and increased fracture risk. Strontium ranelate (SrR) is an effective treatment for postmenopausal and male osteoporosis. To date, no data exist on the use of SrR in the treatment of TM-related osteoporosis.
View Article and Find Full Text PDFBackground: Polycystic ovary syndrome (PCOS) is the most common endocrine cause of menstrual irregularities, hirsutism and acne. Women with PCOS present elevated plasma insulin levels, both fasting and after a glucose load, as an indirect evidence of insulin resistance. PCOS women may also present hypertension, low levels of HDL cholesterol, hypertriglyceridemia, visceral obesity and a higher level of CRP and fibrinogen that can predict an atherosclerotic risk.
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