Publications by authors named "Lucia Libanez Bessa Campelo Braga"
The impact of anxiety and depression on quality of life in a cohort of inflammatory bowel disease patients from Northeastern of Brazil.
Gastroenterol Hepatol
October 2024
Article Synopsis
- - The study investigates the link between chronic illnesses like inflammatory bowel disease (IBD) and the presence of depressive or anxious disorders, aiming to see how these affect patients’ quality of life.
- - A group of 141 patients participated, with data collected on demographics, lifestyle, and mental health using specific questionnaires, revealing that a significant portion suffered from anxiety and depression.
- - Findings suggest that both anxiety and depression significantly lower the quality of life for patients with IBD, regardless of the severity of their illness.
Backgrounds: Fortunately, much has been studied about COVID-19 in patients with inflammatory bowel diseases (IBD). Evidence suggests that these patients do not appear to be at increased risk of severe COVID-19. However, there are still some uncertainties regarding the clinical manifestations of COVID-19 in patients with immune-mediated diseases.
View Article and Find Full Text PDFVaccine adherence and adverse events of the SARS-COV vaccine in patients with inflammatory bowel disease.
Gastroenterol Hepatol
January 2025
Objective: To assess adherence to and the adverse effects of the SARS-COV vaccine in patients with inflammatory bowel disease (IBD).
Patients And Methods: This is an observational, analytical, cross-sectional study. Sociodemographic and clinical data, SARS-COV vaccine data, medications for IBD with use during the vaccination period, and adverse events during the vaccination period were collected.
A MEDICAL AND NEUROPSYCHIATRIC MANAGEMENT SURVEY IN A BRAZILIAN COHORT OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD).
Arq Gastroenterol
March 2024
Background: Inflammatory bowel disease (IBD) can be accompanied by several neurological disorders. Since 2004, we started a Brazilian cohort to assess neuropsychiatric complications in IBD patients. Changes in therapeutic strategy and differences in the prevalence and relevance of neuropsychiatric disorders have been reported in the literature.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to analyze trends and patterns in gastric cancer-related deaths across Brazil from 2000 to 2019, using death certificates as primary data.
- A significant increase in age-adjusted mortality rates was observed, particularly in the less-developed North and Northeast regions, emphasizing socioeconomic disparities in health outcomes.
- The findings highlighted specific high-risk areas for gastric cancer-related mortality, necessitating the implementation of targeted health interventions in these regions to address the growing issue.
Clarithromycin-resistant H. pylori primary strains and virulence genotypes in the Northeastern region of Brazil.
Rev Inst Med Trop Sao Paulo
July 2022
The increase of H. pylori resistance to clarithromycin is a concern. This study evaluated the prevalence of H.
View Article and Find Full Text PDFBackground: Although, outer membrane protein OipA of Helicobacter pylori has been associated with gastric mucosal damage and gastroduodenal diseases, studies evaluating gastric cancer patients are scarce. We investigated whether the functional oipA "on" status was associated with gastric cancer in the North-eastern Brazil, region with high prevalence of gastric cancer.
Methods: We included samples from 95 H.
Background: Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. However, population-based data on GC mortality dynamics in low and middle income countries are scarce.
Methods: We analyzed GC mortality in Brazil based on all GC-related deaths registered 2000-2015.
Background: Inflammatory bowel disease (IBD) is associated with delay in gastric emptying, increase in ghrelin, and decrease in leptin. The aim was to investigate the correlation between gastroduodenal (GD) symptoms, gastric emptying, and serum levels of active ghrelin and leptin in IBD. Twenty-seven IBD patients and 26 healthy volunteers were asked to complete the Porto Alegre Dyspeptic Symptoms Questionnaire.
View Article and Find Full Text PDFPEGYLATED INTERFERON AND RIBAVIRIN FOR TREATMENT OF RECURRENT HEPATITIS C AFTER LIVER TRANSPLANTATION: a single-liver transplant center experience in Brazil.
Arq Gastroenterol
April 2016
Background: Treatment of hepatitis C virus infection in post-transplantation patients is a challenge due to poor tolerance and low success rates.
Objective: To determine the response rate to pegylated interferon and ribavirin in post-liver transplant patients with hepatitis C recurrence.
Methods: Between 18 May 2002 and 18 December 2011, 601 patients underwent liver transplantation at our service (Hospital Universitário Walter Cantídio, University of Ceará), 176 (29.
CagA phosphorylation EPIYA-C motifs and the vacA i genotype in Helicobacter pylori strains of asymptomatic children from a high-risk gastric cancer area in northeastern Brazil.
Mem Inst Oswaldo Cruz
December 2014
Helicobacter pylori infection is one of the most common infections worldwide and is associated with gastric diseases. Virulence factors such as VacA and CagA have been shown to increase the risk of these diseases. Studies have suggested a causal role of CagA EPIYA-C in gastric carcinogenesis and this factor has been shown to be geographically diverse.
View Article and Find Full Text PDFCo-morbid auto-immune disorders may affect 0.2% of the population. We present the clinical and electrodiagnostic findings of 2 patients with inflammatory bowel disease and myasthenia gravis from a Brazilian cohort of 218 inflammatory bowel disease patients.
View Article and Find Full Text PDFThe spectrum of non alcoholic fatty liver disease in morbidly obese patients: prevalence and associate risk factors.
Acta Cir Bras
November 2013
Article Synopsis
- The study aimed to find out how common non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are among morbidly obese patients about to have bariatric surgery and to pinpoint related risk factors.
- A liver biopsy performed on 60 patients revealed that 95% had NAFLD, with 66.7% diagnosed with NASH; only a small number showed severe liver damage (3 patients with fibrosis).
- The findings indicate that NAFLD is prevalent in morbidly obese patients, and the enzyme γGT was identified as a key predictor of the level of fat in their livers.
Helicobacter pylori vacA and cagA genotypes in patients from northeastern Brazil with upper gastrointestinal diseases.
Mem Inst Oswaldo Cruz
June 2012
Article Synopsis
- Helicobacter pylori is linked to chronic gastric inflammation and increases the risk of duodenal and gastric ulcers, as well as gastric cancer.
- This study assessed H. pylori genotypes in 134 Brazilian patients with varied gastric conditions, finding the s1m1 vacA variant was most common and associated with more severe diseases.
- The presence of the cagA gene and mixed vacA strains were significantly linked to gastric cancer and peptic ulcers, indicating that more virulent H. pylori strains are prevalent in regions with high gastric cancer rates in northeastern Brazil.
Diagnosis of spontaneous bacterial peritonitis in cirrhotic patients in northeastern Brazil by use of rapid urine-screening test.
Sao Paulo Med J
May 2006
Context And Objective: Spontaneous bacterial peritonitis (SBP) is a frequent and severe complication of cirrhotic patients with ascites. It has been proposed that the reagent strip for leukocyte esterase designed for the testing of urine (Combur test UX) could be a useful tool for diagnosing SPB. The aim of this study was to assess the sensitivity and specificity of urine test strips for diagnosing SBP in cirrhotic patients with ascites.
View Article and Find Full Text PDFHelicobacter pylori eradication using tetracycline and furazolidone versus amoxicillin and azithromycin in lansoprazole based triple therapy: an open randomized clinical trial.
Arq Gastroenterol
December 2005
Background: Optimal anti-Helicobacter pylori treatment has not yet been established.
Aim: To evaluate H. pylori eradication using tetracycline and furazolidone versus amoxicillin and azithromycin in lansoprazole based triple therapy in northeastern of Brazil.