Inverted meniscus IOLs reduce image shifts in the periphery compared to biconvex IOLs.

Intraocular lenses (IOLs) are routinely used to replace cataractous crystalline lenses. Most current models have a biconvex design that reduces optical quality in the periphery since they are optimized only for central vision. Inverted meniscus IOLs are optimized to achieve similar optical performance to phakic eyes in the peripheral retina.

Peripheral Vision in Patients Following Intraocular Lens Implantation: A Systematic Review and Meta-Analysis.

Purpose: To update the literature on peripheral optics and vision following intraocular lens (IOLs) implantation.

Methods: We investigated how current IOLs influence peripheral visual function, peripheral optical quality, and visual perception and performance, in patients following cataract surgery. Peripheral vision is described as vision outside the central foveal region of the eye (beyond 4-5° of eccentricity).

Peripheral Refraction and Contrast Detection Sensitivity in Pseudophakic Patients Implanted With a New Meniscus Intraocular Lens.

Purpose: To evaluate peripheral refraction and contrast detection sensitivity in pseudophakic patients implanted with a new type of inverted meniscus intraocular lens (IOL) (Art25; Voptica SL) that was designed to provide better peripheral optics.

Methods: One month after cataract surgery, in 87 eyes implanted with the Art25 IOL, peripheral contrast detection sensitivity was measured psychophysically at 40° visual angle, both horizontally and vertically, and compared with a control group of 51 eyes implanted with standard biconvex IOLs. Thirty-one eyes with the Art25 IOL and 28 eyes from the control group were randomly selected to also measure peripheral refraction using a scanning Hartmann-Shack wavefront sensor along 80° in the horizontal meridian.

Spherical Aberration Customization to Extend the Depth of Focus With a Clinical Adaptive Optics Visual Simulator.

Purpose: To evaluate the use of the VAO adaptive optics visual simulator (Voptica SL, Murcia, Spain) for customization of spherical aberration to increase depth of focus.

Methods: Through-focus visual acuity with both high- and low-contrast letters from +1.00 to -3.

Effect of Crystalline Lens Aberrations on Adaptive Optics Simulation of Intraocular Lenses.

Purpose: To evaluate the impact of the lens aberrations on the adaptive optics visual simulation of pseudophakic intraocular lens (IOL) profiles.

Methods: In 20 right phakic eyes, lens higher order aberrations (HOAs) were calculated as the whole eye minus the corneal aberrations. Visual simulation using low and high contrast corrected distance visual acuity (CDVA) testing was carried out with the VAO instrument (Voptica, SL, Murcia, Spain), considering three optical conditions of the lens: removing HOA (no lens-HOA), removing spherical aberration (no lens-SA), and with lens HOA (natural condition).

Assessment of subjective refraction with a clinical adaptive optics visual simulator.

Purpose: To clinically validate an adaptive optics visual simulator (VAO) that measures subjective refraction and visual acuity.

Setting: Optics Laboratory, University of Murcia, Murcia, Spain.

Design: Prospective case series.

Micrometric Control of the Optics of the Human Eye: Environment or Genes?

Purpose: The human eye has typically more optical aberrations than conventional artificial optical systems. While the lower order modes (defocus and astigmatism) are well studied, our purpose is to explore the influence of genes versus the environment on the higher order aberrations of the optical components of the eye.

Methods: We have performed a classical twin study in a sample from the Region of Murcia (Spain).

Optical Measurement of Straylight in Eyes With Cataract.

Purpose: To measure straylight in a cohort of patients with cataract using a novel optical instrument and to correlate optical straylight values with clinical grade of cataracts and psychophysical straylight values.

Methods: Measurements were performed on 53 eyes of 44 patients with cataract admitted to the ophthalmology service of the university hospital in Murcia, Spain, and 9 young volunteers with no known ophthalmic pathology. Lens opacities were classified according to the Lens Opacities Classification System Ill (LOCS III) under slit-lamp examination.

The accommodative ciliary muscle function is preserved in older humans.

Presbyopia, the loss of the eye's accommodation capability, affects all humans aged above 45-50 years old. The two main reasons for this to happen are a hardening of the crystalline lens and a reduction of the ciliary muscle functionality with age. While there seems to be at least some partial accommodating functionality of the ciliary muscle at early presbyopic ages, it is not yet clear whether the muscle is still active at more advanced ages.

Environmental and Genetic Factors Explain Differences in Intraocular Scattering.

Purpose: To study the relative impact of genetic and environmental factors on the variability of intraocular scattering within a classical twin study.

Methods: A total of 64 twin pairs, 32 monozygotic (MZ) (mean age: 54.9 ± 6.