Publications by authors named "Lucia G Gonzalez"
Does HER2 status influence in the benefit of ramucirumab and paclitaxel as second line treatment of advanced gastro-esophageal adenocarcinoma? Data from the AGAMENON-SEOM registry.
J Cancer Res Clin Oncol
July 2023
Article Synopsis
- The study compared the effectiveness of ramucirumab-paclitaxel versus traditional chemotherapy in second-line treatment for advanced gastroesophageal cancer (aGEC), focusing on patients' HER2 status.
- Patients from the AGAMENON-SEOM registry treated between 2016 and 2021 were analyzed for progression-free survival (PFS) and overall survival (OS) using statistical methods.
- Results indicated that ramucirumab-paclitaxel significantly improved both PFS and OS compared to chemotherapy, regardless of HER2 status, highlighting its potential as a better treatment option for aGEC patients.
The aim of this study was to evaluate the efficacy and safety of outpatient antimicrobial therapy with piperacillin-tazobactam in continuous infusion using elastomeric pumps and to evaluate the economic impact compared with conventional hospital treatment in patients with Pseudomonas aeruginosa (PA) infections. This is an observational study. Patients with PA infection treated with continuous piperacillin-tazobactam infusion using elastomeric pumps in our hospital between January 2015 and December 2017 were included.
View Article and Find Full Text PDFMalaria is an infectious illness, affecting vulnerable populations in Third World countries. Inspired by natural products, indole alkaloids have been used as a nucleus to design new antimalarial drugs. So, eighteen oxindole derivatives, analogues were obtained with moderate to excellent yields.
View Article and Find Full Text PDFCutaneous larva migrans (CLM) represents the most common tropically acquired dermatosis. CLM is caused by infection with hookworm larvae in tropical and sub-tropical areas, and people who have a history of foreign travel and of walking barefoot on sandy soil or beaches are at a high risk of getting infected with it. The diagnosis is usually made on the basis of the typical appearance of the lesion, intense itching and history of foreign travel.
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