Clusterin levels in undernourished SH-SY5Y cells.

Food-related disorders are increasingly common in developed societies, and the psychological component of these disorders has been gaining increasing attention. Both overnourishment with high-fat diets and perinatal undernourishment in mice have been linked to a higher motivation toward food, resulting in an alteration in food intake. Clusterin (CLU), a multifaced protein, is overexpressed in the (NAc) of over-fed rats, as well as in those that suffered chronic undernutrition.