Publications by authors named "Lucia Baixauli Marin"
Objective: To characterize inflammatory and mechanical changes in the collagenase-induced OA (CIOA) model in rats.
Design: Skeletally mature, 6-month-old Wistar rats received unilateral intraarticular injections of saline, 500 U or 1000 U of collagenase on days 0 and 2 of the study. Joint tissues were harvested on either day 4 or 70 to evaluate the acute and long-term changes.
Assessment of whole cartilage surface damage in an osteoarthritis rat model: The Cartilage Roughness Score (CRS) utilizing microcomputed tomography.
Sami Kauppinen David Fercher Gonçalo Barreto Ville-Pauli Karjalainen Vesa Virtanen Lucia Baixauli-Marin Marina Fonti
Osteoarthritis Cartilage
January 2025
Article Synopsis
- This study looks for a good way to find early signs of cartilage damage in osteoarthritis using rats as models.
- Researchers developed a new scoring system called Cartilage Roughness Score (CRS) to measure damage and compared it with a traditional method.
- The results showed that CRS works better than the old method and can help track how quickly cartilage gets worse over time.