Subcutaneous, Oral, and Intranasal Immunization of BALB/c Mice with K39 Antigen Induces Non-Protective Humoral Immune Response.

Visceral leishmaniasis is a high-burden disease caused by parasites of the genus. The K39 kinesin is a highly antigenic protein of , but little is known about the immune response elicited by this antigen. We evaluated the humoral immune response of female BALB/c mice ( = 6) immunized with the rK39-HFBI construct, formed by the fusion of the K39 antigen to a hydrophobin partner.