Publications by authors named "Luce Yemadje Menudier"

Liver involvement is an unusual yet frequently overlooked dengue complication. Pivotal for an efficient clinical management, the early diagnosis of dengue-associated liver involvement relies on an accurate description of its clinical and biological characteristics, its prognosis factors, its association with severe dengue and its clinical management. We conducted a systematic review by searching PubMed and Web of Science databases for original case reports, cohort and cross-sectional studies reporting the clinical and/or biological features of dengue-associated liver involvement.

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Article Synopsis
  • Island communities provide a unique setting for studying microbial evolution during epidemics due to their limited population connectivity, as seen on Reunion Island during the early COVID-19 pandemic.
  • In 2021, the SARS-CoV-2 Beta variant surged in Reunion Island before being replaced by the Delta variant, highlighting the island's role in genomic evolution.
  • The isolation of islands can lead to the emergence of distinct genetic lineages, making them important areas for understanding the ongoing evolution and spread of COVID-19 variants.
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Background: Dengue is the world's most prevalent mosquito-borne viral disease. It is endemic in many tropical and subtropical countries and represents a significant global health burden. The first reports of dengue virus (DENV) circulation in the South West Indian Ocean (SWIO) islands date back to the early 1940s; however, an increase in DENV circulation has been reported in the SWIO in recent years.

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In January 2021, after detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, genomic surveillance was established on Réunion Island to track the introduction and spread of SARS-CoV-2 lineages and variants of concern. This system identified 22 SARS-CoV-2 lineages, 71% of which were attributed to the Beta variant.

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