Int J Clin Pharm
August 2023
Background: Algorithms for causality assessment of adverse drug reactions (ADRs) in a neonatal intensive care unit (NICU) are important in the management of adverse events, however, it is inconclusive which tool best suits pharmacovigilance in neonates.
Aim: To compare the performance of the algorithms of Du and Naranjo in determining causality in cases of ADRs in neonates in a NICU.
Method: This observational and prospective study was conducted in a NICU of a Brazilian maternity school between January 2019 and December 2020.