Publications by authors named "Lucas Spindler"
Background: Pilonidal disease (PD) is a common condition for which the global incidence is increasing. Surgery is the currently preferred approach to treatment but there is a growing interest in new minimally invasive techniques, such as sinus laser therapy (SiLaT).
Aim: Our primary objective was to assess the efficacy of SiLaT for the treatment of pilonidal disease.
Article Synopsis
- High-resolution anoscopy (HRA) is essential for detecting and treating precursors of anal squamous cell carcinoma (ASCC), and AI algorithms can effectively distinguish between high-grade and low-grade squamous lesions in HRA images.
- A deep learning system using a convolutional neural network (CNN) was developed, trained on 151 HRA exams comprising over 57,000 images to automate the differentiation between high-grade squamous intraepithelial lesions (HSIL) and low-grade lesions (LSIL).
- The CNN achieved high accuracy rates, with an overall accuracy of 94.6%, and demonstrated sensitivity and specificity of 93.6% and 95.7%, respectively, indicating its potential to improve early
Introduction: There are very few French studies on hemorrhoidal disease and its management.
Patients And Methods: Prospective single-center study from July to December 2021 including 472 patients.
Results: Bleeding, prolapse and pain were the main reasons for consultation.
PLACE DE L'IRM POUR EXPLORER LES PATHOLOGIES ANORECTALES. L'imagerie par résonance magnétique (IRM) est l'un des examens d'imagerie les plus utiles à l'exploration des pathologies ano rectales. Elle est complémentaire de l'examen clinique et de l'endo scopie.
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- High-resolution anoscopy (HRA) is crucial in identifying precursors to anal squamous cell carcinoma, and AI models show potential for improving this process, though previous studies haven't looked at how staining and anal manipulation affect them.
- A convolutional neural network was created using 27,770 images to distinguish between high-grade and low-grade lesions, achieving an impressive overall accuracy of 98.3% across various image subsets.
- The AI demonstrated standout sensitivity and specificity, and its effectiveness varied based on the type of staining used, suggesting that AI could significantly enhance the accuracy and efficiency of HRA procedures in real time.
Aim: The aim of this study was to evaluate the real-life clinical and radiological efficacy of darvadstrocel injection into complex perianal fistulas in Crohn's disease. Secondary endpoints were to assess symptomatic efficacy, adverse effects and factors associated with complete combined clinical-radiological response (deep remission).
Methods: After marketing the product in France, all first patients treated consecutively were included.
MANAGEMENT OF SECONDARY LESIONS IN ANO-PERINEAL CROHN'S DISEASE. Anoperineal involvement in Crohn's disease is common and affects around 1/3 of patients during their disease. It constitutes a pejorative factor with an increased risk of permanent colostomy and proctectomy and is associated with a major deterioration in quality of life.
View Article and Find Full Text PDFTHE REVOLUTION IN MINIMALLY INVASIVE SURGERY. Pilonidal disease is a common suppurative condition and affects 0.7% of the population.
View Article and Find Full Text PDFSPARING THE SPHINCTER. Fistulotomy is the most used treatment for anal fistula. It is very effective with a cure rate of over 95% but carries a risk of incontinence.
View Article and Find Full Text PDFIntroduction: for localized T1N0 squamous cell carcinoma of the anus (SCCA) standard radiotherapy (RT) may result in overtreatment and alternative strategies are debated.
Methods: T1N0M0 SCCA treated between 2015 and 2020 by local excision (LE) or RT were analyzed from the French prospective FFCD ANABASE cohort. Treatment strategies, recurrence-free and colostomy-free survivals (RFS, CFS) and prognostic factors were reported.
Anal fissure. Anal fissure is a painful proctological disease that most often affects young patients equally in both sexes. It significantly worsens the quality of life and requires rapid care.
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