Publications by authors named "Lucas R M de Andrade"

The assessment of ricinoleic acid (RA) incorporated into polymeric nanoparticles is a challenge that has not yet been explored. This bioactive compound, the main component of castor oil, has attracted attention in the pharmaceutical field for its valuable anti-inflammatory, antifungal, and antimicrobial properties. This work aims to develop a new and simple analytical method using high-performance liquid chromatography with diode-array detection (HPLC-DAD) for the identification and quantification of ricinoleic acid, with potential applicability in several other complex systems.

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Hydrogels are a great ally in the pharmaceutical and biomedical areas. They have a three-dimensional polymeric structure that allows the swelling of aqueous fluids, acting as an absorbent, or encapsulating bioactive agents for controlled drug release. Interestingly, plants are a source of biogels, specifically polysaccharides, composed of sugar monomers.

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Article Synopsis
  • Repellents are crucial in preventing diseases from Aedes aegypti mosquitoes, but their high concentrations can be harmful, especially for children and pregnant women.
  • The study focused on creating polymeric nanocapsules for the repellents geraniol and icaridin using lower concentrations to enhance efficacy and reduce toxicity.
  • Results showed the nanocapsules had favorable sizes, high encapsulation efficiency, stable physicochemical properties, and did not negatively impact cell viability or DNA, indicating their potential as effective and safe mosquito repellents.
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Natural polysaccharides are structures composed of highly diversified biological macromolecules whose properties have been exploited by a diversity of industries. Until 2018, the polysaccharides market raised more than US $ 12 billion worldwide, while an annual growth forecast of 4.8% is expected by 2026.

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Multi-Walled Carbon Nanotubes (MWCNT) have been functionalized with rutin through three steps (i. reaction step; ii. purification step; iii.

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