Publications by authors named "Lucas Lopes Leon"
Article Synopsis
- The study focuses on determining how prevalent and impactful DNA viral infections are in children with nephrotic syndrome (NS), specifically looking at various viruses like Epstein-Barr and cytomegalovirus.
- Researchers conducted a prospective study involving 35 NS patients aged 1 to 18, monitoring viral presence in plasma and urine over an average of 266 days, finding that 31.4% had active viral infections.
- Notably, HCMV was the most common infection linked to increased proteinuria and hospitalization rates, highlighting its significance in worsening NS in pediatric patients.
Introduction: Herpesviruses, enteroviruses, and arboviruses are important because of their clinical relevance and ability to cause meningitis, encephalitis, meningoencephalitis, and other diseases. The clinical virology associated with diagnostic technologies can reduce the morbidity and mortality of such neurological manifestations. Here we aimed to identify the genomes of agents that cause neurological syndromes in cerebrospinal fluid (CSF) samples from patients with suspected nervous system infections admitted to the University Hospital of the University of Campinas, São Paulo, Brazil, in 2017-2018.
View Article and Find Full Text PDFAn amendment to this paper has been published and can be accessed via the original article.
View Article and Find Full Text PDFBackground: Human herpesviruses (HHVs) are responsible for a significant number of clinical manifestations in systemic lupus erythematous (SLE) patients. The aim of this study was to determine the frequency of active HHV infections in SLE patients and correlating them with disease activity.
Methods: Serum samples were collected from 71 SLE patients and their DNAs were extracted and analyzed to detect HHV-DNA viruses using the nucleic acid amplification technique.