ChatGPT and dentistry: a step toward the future.

This article aims to explore the integration of ChatGPT, an advanced conversational artificial intelligence model, in the field of dentistry. The review primarily consists of information related to the capabilities and functionalities of ChatGPT and how these abilities can aid dental professionals. This study includes data from research papers, case studies, and relevant literature on language models, as well as papers on dentistry, patient communication, dental education, and clinical decision-making.

The use of deep learning state-of-the-art architectures for oral epithelial dysplasia grading: A comparative appraisal.

Background: Dysplasia grading systems for oral epithelial dysplasia are a source of disagreement among pathologists. Therefore, machine learning approaches are being developed to mitigate this issue.

Methods: This cross-sectional study included a cohort of 82 patients with oral potentially malignant disorders and correspondent 98 hematoxylin and eosin-stained whole slide images with biopsied-proven dysplasia.

Symptomatic subgemmal neurogenous plaque in patients with COVID-19: Is there an association?

Background: Subgemmal neurogenous plaques (SNP) are composed of neural structures found in the posterolateral portion of the tongue, rarely biopsied as most of them are asymptomatic or eventually only clinically managed. We aimed to investigate a case series of possible correlation of symptomatic subgemmal neurogenous plaque (SNP) with coronavirus disease 2019 (COVID-19).

Methods: Eleven formalin-fixed paraffin-embedded cases from patients with previous confirmed COVID-19 (by RT-PCR) were retrieved from two pathology files.

Machine learning for detection and classification of oral potentially malignant disorders: A conceptual review.

Oral potentially malignant disorders represent precursor lesions that may undergo malignant transformation to oral cancer. There are many known risk factors associated with the development of oral potentially malignant disorders, and contribute to the risk of malignant transformation. Although many advances have been reported to understand the biological behavior of oral potentially malignant disorders, their clinical features that indicate the characteristics of malignant transformation are not well established.

Hybrid odontogenic lesions: A systematic review of 203 cases reported in the literature.

Background: Hybrid odontogenic lesions combine histopathological characteristics of two or more odontogenic cysts and/or tumours. The aim of this study was to evaluate the available data on hybrid odontogenic lesions (HOL) and to analyse their epidemiological/clinical features and biological behaviour.

Methods: An electronic search was done in January 2021 using multiple databases.

Odontogenic Keratocyst in a 9-Month-Old Patient: A Case Report.

Odontogenic Keratocyst (OKC) is a benign, intraosseous, odontogenic cyst which originates from the basal cells of overlying epithelium or from the dental lamina remnants. Clinically, they are presented as asymptomatic swellings, although can sometimes be associated with pain. Growth of an OKC leads to expansion and destruction of bone as it infiltrates the tissue around it.

Oral and oropharyngeal lymphomas: A multi-institutional collaborative study.

Background: Lymphomas in the oral and oropharyngeal regions are relatively uncommon, and their diagnosis is challenging and complex due to the myriad histopathological subtypes. Herein, we report a large series of oral and oropharyngeal lymphomas and compare our data with the currently available literature.

Methods: All cases diagnosed as lymphomas affecting the oral and oropharyngeal regions were retrospectively retrieved from seven Brazilian institutions.

HIV-positive patients with oral Kaposi's sarcoma: An overall survival analysis of 31 patients.

Objective: The aim of this study was to evaluate the influence of viral load and lymphocyte count on survival of patients who presented with human immunodeficiency virus (HIV)-associated oral Kaposi's sarcoma.

Study Design: Thirty-one cases (from January 2010 to December 2019) of oral Kaposi's sarcoma in patients with HIV from 2 oral pathology centers in Brazil were reviewed, considering clinical data and correlation of viral load and lymphocyte count with overall survival. Overall survival rates were estimated by a Kaplan-Meier analysis and compared using a log-rank test.

Oral and oropharyngeal diffuse large B-cell lymphoma and high-grade B-cell lymphoma: A clinicopathologic and prognostic study of 69 cases.

Objective: The objective of this study was to describe the clinicopathological, molecular, and prognostic features of oral/oropharyngeal diffuse large B-cell lymphoma (DLBCL) and high-grade B-cell lymphoma.

Study Design: All cases were retrieved from 7 Brazilian institutions. Immunohistochemical reactions were performed to confirm the diagnoses and to categorize the tumors.

Significance of Expression and Loss of Heterozygosity in Human Papilloma Virus-related Oral Squamous Cell Carcinoma.

Background/aim: p16 and PTEN are tumor suppressor genes. Loss of these molecules in oral squamous cell carcinoma (OSCC) has been studied worldwide. In this study, we explored whether p16 cooperates with inactive PTEN during the pathogenesis of OSCC, especially in regard to tumor aggressiveness and proliferation.

A multicenter study of oral sarcomas in Brazil.

Objectives: The aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil.

Materials And Methods: A cross-sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres. Gender, age, evolution time, clinical aspects, tumour location, tumour size at diagnosis, radiographic aspects and histopathological diagnosis were evaluated.

Mandibular lesion as the first sign of multiple myeloma in a young patient.

Multiple myeloma (MM) is a malignant neoplasm characterized by an abnormal intramedullary plasma cell proliferation. It accounts for approximately 10% of all hematologic malignancies. It generally occurs between fourth and seventh decades of life, and it is predominant in male patients.

Evaluation of tumor-infiltrating lymphocytes in osteosarcomas of the jaws: a multicenter study.

The aim of the present study was to investigate the profile of tumor-infiltrating lymphocytes (TIL) in osteosarcomas of the jaws (OSJ). A total of 21 OSJ samples were analyzed in a retrospective and cross-sectional multicenter study. Immunohistochemistry was performed to determine the recognition of TIL such as CD4, CD8, granzyme B (GrB), programmed cell death protein (PD-1), and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) in intratumoral and peripheral (stromal) regions.

Clinicopathological analysis of oral diffuse large B-cell lymphoma, NOS: A systematic review.

Background: Diffuse large B-cell lymphoma, NOS (DLBCL NOS) is the commonest extranodal non-Hodgkin lymphoma diagnosed in the oral and maxillofacial region. However, few studies are currently available and its prognostic determinants remain undefined.

Purpose: To analyse the available data on oral DLBCL NOS and to describe its clinicopathological features, identifying potential prognostic factors.

Melanotic neuroectodermal tumor of infancy of the jaw bones: Update on the factors influencing survival and recurrence.

The aim of the present study was to integrate the available data published on melanotic neuroectodermal tumor of infancy (MNTI) of the jaw bones. An electronic search was undertaken in April 2018. Hundred forty-seven publications and 371 patients were included.

Congenital Ranula: A Case Report and Literature Review.

Ranula consists of a pathological process induced by ductal disruption of the minor salivary glands followed by extravasation of mucous material surrounding adjacent structures. A swelling causing breathing and feeding problems associated with tongue displacement is frequently observed. It is a disease that generally involves the younger age group.

Clinicopathological analysis of oral plasmablastic lymphoma: A systematic review.

Background: Plasmablastic lymphoma (PBL) is a high-grade lymphoma that often affects the oral cavity of HIV-positive patients; however, its prognostic determinants remain unknown.

Purpose: To integrate the available data on oral PBL to determine its clinicopathological features and to identify potential prognostic factors.

Methods: An electronic systematic review was performed using multiple databases with a specific search strategy in February 2018.