MRSA strains with distinct accessory genes predominate at different ages in cystic fibrosis.

Rationale: Methicillin resistant Staphylococcus aureus (MRSA) is prevalent and consequential in cystic fibrosis (CF). Whole genome sequencing (WGS) could reveal genomic differences in MRSA associated with poorer outcomes or detect MRSA transmission.

Objectives: To identify MRSA genes associated with low lung function and potential MRSA transmission in CF.

Sustained Coinfections with and in Cystic Fibrosis.

: and often infect the airways in cystic fibrosis (CF). Because registry studies show higher prevalence of versus in older patients with CF, a common assumption is that replaces over time. , can outgrow and kill .