Publications by authors named "Lucas Gorza"

Article Synopsis
  • Recreational use of nitrous oxide (NO) has led to a rise in severe neurological disorders, particularly affecting young adults in economically disadvantaged areas.
  • The study analyzed 181 patients, noting a significant incidence increase in 2020-2021, especially in those aged 20-25.
  • Compared to other inflammatory neurological disorders, NI-NDs were found to be two to three times more common in these vulnerable populations.
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Article Synopsis
  • Mononeuritis multiplex is a rare but severe side effect associated with immune checkpoint inhibitors, particularly noted in three patients with mesothelioma in a French study.
  • The study involved three elderly male patients who exhibited severe neurological symptoms and were diagnosed with mononeuritis multiplex after receiving treatment with nivolumab and ipilimumab.
  • All patients were treated with corticosteroids, resulting in improvements, but one patient required additional therapy (rituximab and cyclophosphamide) after symptom recurrence upon tapering steroids.
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Objectives: To provide an overview of the spectrum, characteristics and outcomes of neurologic manifestations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Methods: We conducted a single-centre retrospective study during the French coronavirus disease 2019 (COVID-19) epidemic in March-April 2020. All COVID-19 patients with de novo neurologic manifestations were eligible.

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