Publications by authors named "Lucas Ferreira Fagundes Ouverney"
Transplant Proc
February 2024
Article Synopsis
- Intestinal transplantation (IT) and multivisceral transplantation (MVT) are effective treatments for patients suffering from intestinal failure due to complications from total parenteral nutrition, requiring high levels of immunosuppression to prevent acute cellular rejection (ACR).
- A review of literature from 2006 to 2022 revealed 14 key studies that highlighted the most effective immunosuppressants for induction and maintenance, identifying thymoglobulin, tacrolimus, and corticosteroids as the main components of therapy.
- The findings suggest that the optimal immunosuppressive protocol is a triple therapy involving thymoglobulin for induction and a combination of tacrolimus and mycophenolate with corticosteroids for maintenance, with a focus
