Episodic consumption of high doses of alcohol in a short period (binge drinking - BD) among adolescents is known to be harmful to their brain development. Chronic use of taurine increases voluntary alcohol consumption and shows an anxiolytic-like effect in rats. In this study, we evaluated the differential effects of chronic and intermittent taurine administration on alcohol consumption and behavioral changes in adolescent and young adult rats subjected to the BD model.
View Article and Find Full Text PDFBackground: The effects of tobacco smoke on the central nervous system are usually studied with isolated nicotine, ignoring other compounds present in cigarette smoke. The few studies that use in vivo whole-body cigarette smoke exposure are usually performed in expensive commercial apparatus.
New Method: We presented a feasible, safe, and low-cost apparatus for cigarette smoke exposure in rodents.
Chronic opioid use changes brain chemistry in areas related to reward processes, memory, decision-making, and addiction. Both neurons and astrocytes are affected, ultimately leading to dependence. Passiflora incarnata L.
View Article and Find Full Text PDFTaurine is an amino acid usually added to energy drinks. In rodents, acute taurine administration decreases voluntary alcohol intake, and subchronic administration restores different behavioral features impaired by alcohol withdrawal. In the present study, we evaluated the effects of chronic taurine treatment on voluntary alcohol consumption and changes in behavioral parameters in rats.
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