Publications by authors named "Lucas Conzatti"

Article Synopsis
  • This study investigates the link between oral inflammatory burden (OIB) and carotid atherosclerotic burden (CAB) in patients who have experienced ischemic stroke (IS) or transient ischemic attack (TIA).
  • A total of 240 hospital patients were analyzed, focusing on dental conditions like apical periodontitis and root canal treatment, to determine their relationship with the severity of CAB.
  • Results indicate that higher levels of OIB correlate with increased CAB, suggesting a significant interaction between oral and cardiovascular health that merits further exploration.
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Article Synopsis
  • - The study investigated the link between the number of permanent natural teeth and the risk of ischemic stroke (IS) or transient ischemic attack (TIA) in a southern Brazilian population, involving 458 participants.
  • - Participants included 229 individuals with IS or TIA (cases) and 229 without cardiovascular disease (controls), matched by age and sex, with assessments using advanced imaging techniques.
  • - Results indicated that fewer natural teeth were associated with a higher risk of IS or TIA, along with factors like hypertension and smoking, suggesting oral health may play a significant role in cardiovascular events.
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Objectives: The purpose of the study was twofold: (1) to test the hypothesis that tooth loss is independently associated with carotid atherosclerotic burden (CAB) among individuals with ischemic stroke (IS) or transient ischemic attack (TIA) and (2) to test the association between tooth loss and disability following the occurrence of cerebral ischemia.

Materials And Methods: This observational study included 418 patients with IS or TIA. Tooth loss and the CAB were measured through a head and neck multidetector computed tomography angiography.

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The identification of autoantibodies in central nervous system (CNS) inflammatory disorders improves diagnostic accuracy and the identification of patients with a relapsing disease. Usual methods to detect autoantibodies are usually divided into 3 categories: tissue-based assays, protein-based assays and cell-based assays (CBA). Tissue-based assays are commonly used for initial identification of autoantibodies based on staining patterns and co-localization.

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Background: Infertility is one of many complications of spinal cord injury (SCI) in male patients, who are often at the peak of their reproductive life. This study evaluated effects of hyperbaric therapy (HT) on quality of sperm of rats with SCI and correlated the findings with histologic analysis of the testicles.

Methods: This experimental study comprised 18 rats that were submitted to SCI with a MASCIS Impactor and randomly allocated to either a HT or a control group.

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Background: The corpus callosum index (CCI) can be easily and reliably obtained from conventional magnetic resonance imaging (MRI) and has been proposed as a possible marker of brain atrophy in MS. However, further validation of its correlation with volumetric measurements is still warranted.

Objective: To assess the correlation of the CCI with the corpus callosum volume (CCV), brain and lesion volumes, and level of disability in MS.

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Study Design: A controlled laboratory study.

Objective: The aim of this study was to analyze the effectiveness of hyperbaric therapy (HT) using mild and moderate models of spinal cord injury (SCI).

Summary Of Background Data: SCI can cause permanent impairment with socioeconomic consequences.

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Article Synopsis
  • The study assessed the prevalence and characteristics of low back pain (LBP) in a middle-aged population in southern Brazil, revealing that 72% of participants experienced LBP at least once.
  • Most participants were female (61.6%) and had a mean age of 33.74 years, with reported pain intensity averaging 4.51 on a scale.
  • Anxiety was significantly associated with LBP, particularly in individuals under 40, where 69.7% reported experiencing pain.
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Objective: To verify the association between depression and headache in young adults, as well as to identify the features of headache associated with depression and the influence of this mood disorder on headache-related disability.

Methods: A cross-sectional study with self-administered questionnaires about headache and depression was conducted at the Universidade de Caxias do Sul. Beck Depression Inventory (BDI) and Migraine Disability Assessment (MIDAS) were used to evaluate depressive symptoms and headache-related disability, respectively.

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