Publications by authors named "Lucas Bickmann"

Feature attribution methods stand as a popular approach for explaining the decisions made by convolutional neural networks. Given their nature as local explainability tools, these methods fall short in providing a systematic evaluation of their global meaningfulness. This limitation often gives rise to confirmation bias, where explanations are crafted after the fact.

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Extensive research has been conducted on time series and tabular data in the context of classification tasks, considering their distinct data domains. While feature extraction enables the transformation of series into tabular data, direct comparative comparisons between these data types remain scarce. Especially in the domain of medical data, such as electrocardiograms (ECGs), deep learning faces challenges due to its lack of easy and fast interpretability and explainability.

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Deep Learning architectures for time series require a large number of training samples, however traditional sample size estimation for sufficient model performance is not applicable for machine learning, especially in the field of electrocardiograms (ECGs). This paper outlines a sample size estimation strategy for binary classification problems on ECGs using different deep learning architectures and the large publicly available PTB-XL dataset, which includes 21801 ECG samples. This work evaluates binary classification tasks for Myocardial Infarction (MI), Conduction Disturbance (CD), ST/T Change (STTC), and Sex.

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Article Synopsis
  • Interest in machine learning in medicine is rising, but there's a gap between study findings and their clinical application, mainly due to data quality and interoperability issues.
  • The research focuses on differences in publicly available ECG datasets that should be compatible, assessing how small variations in studies impact the reliability of machine learning models.
  • The study evaluates the performance of various machine learning techniques across different datasets to understand how well single-site ECG studies generalize.
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