Whole brain radiotherapy and stereotactic radiosurgery for patients with recursive partitioning analysis I and lesions <5 cm(3): A matched pair analysis.

Objective: The intention of this study is to compare whole brain radiotherapy and stereotactic radiosurgery (WBRT + SRS) with WBRT in patients with 1-4 brain metastases to find a subgroup of patients that have a great benefit with aggressive treatment.

Materials And Methods: Between December 2002 and December 2013, 60 patients with 1-4 brain metastases were treated by WBRT + SRS. In this period, 60 patients treated with WBRT were matched with patients treated with WBRT + SRS.

Patients with N1 breast cancer: who could benefit from supraclavicular fossa radiotherapy?

Purpose: To find a high-risk group of supraclavicular fossa recurrence (SCFR) in N1 breast cancer treated with breast conservative therapy without supraclavicular radiation therapy (SCFRT).

Methods And Materials: We designed a retrospective review of 767 patients with N1 breast cancer. All patients included in this study underwent to lumpectomy or quadrantectomy with axillary lymph node dissection, followed by whole breast irradiation.