The adhesion strength of a bacterial strain on a substrate influences colonization and biofilm development, so the biomolecular analysis of this interaction is a step that allows insights into the development of antifouling surfaces. As peri-implantitis is the main cause of failure of implant-supported oral rehabilitations and the dental literature presents gaps in the atomic bacteria/surface interaction, this study aimed to correlate the qualitative variation of roughness, wettability, chemical composition, and electrical potential of Ti-6Al-4V and Ti-35Nb-7Zr-5Ta (TNZT) disks obtained by machining (M) and additive manufacturing (AM) on the colonization and adhesion strength of S. aureus quantified by atomic force microscopy (AFM).
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