Dolichocarpols G-X: Previously undescribed macrocyclic humulene sesquiterpenoids from Anaxagorea dolichocarpa.

Eleven previously undescribed macrocyclic humulene sesquiterpenoids, dolichocarpols G-Q (1-11), five undescribed bicyclic, dolichocarpols R-V (12-16) and two undescribed norsesquiterpenes, dolichocarpols W-X (17-18) were isolated from the roots of Anaxagorea dolichocarpa. Their structures were unequivocally determined by the analysis of NMR, HRESIMS, and IR data, along with NMR and ECD quantum-mechanical calculations, followed by the application of the DP4+ method. Most compounds possess an ether bridge between different carbons, whereas compounds 13/14 and 15/16 are diastereomers isomerized at C-7/C-10 and at C-7/C-10/C-12, respectively.

Oral and Maxillofacial Manifestations of Kallmann Syndrome: A Systematic Analysis of the Literature.

Aims: Kallmann syndrome (KS) is a rare genetic disorder characterized by congenital hypogonadotropic hypogonadism and varied clinical features. Despite its recognition, the oral and maxillofacial manifestations remain poorly understood. This study synthesized clinical aspects and management of KS-related oral and maxillofacial alterations.

Mast cells and factor XIIIa+ dendrocytes in actinic cheilitis and lip squamous cell carcinoma.

There is an interaction between dendrocytes and mast cells in the skin. However, in elastosis-related diseases such as actinic cheilitis (AC) and lower lip squamous cell carcinoma (LLSCC), this interaction remains unknown. We investigated the presence of intact and degranulated mast cells in AC and LLSCC.

Complete genome of pv. strain CCRMTAQ13 (causal agent of angular leaf spot in cashew) from Brazil using long-read Nanopore technology.

Here, we present a single contiguous genome sequence of pv. (; strain CCRMTAQ13), the causal agent of angular leaf spot in cashew, an important commodity crop in Brazil. Oxford Nanopore Sequencing Technology was used to assemble the genome of the in a single contig of 5,086,757 bp with a 64.

Leukemia and Lymphoma Mimicking Periapical Conditions Resulting in Endodontic Treatment: A Systematic Review.

Introduction: Leukemia and lymphoma mimicking periapical conditions can lead to significant diagnostic pitfalls. Guidance for endodontists in managing such cases is barely explored. This systematic review aimed to summarize the clinicopathologic, imaging, and management aspects of leukemia/lymphoma that mimicked periapical conditions and resulted in endodontic treatment.

Dental and Craniofacial Anomalies in Fanconi Anemia: A Systematic Review and Additional 46 Reports.

Objective: Fanconi anemia (FA), a rare genetic disorder, has not been comprehensively studied regarding its dental and craniofacial phenotypes. This study aimed to systematically review the available evidence on dental, occlusion, and craniofacial anomalies in individuals with FA and to describe the occurrence of these anomalies in a cohort from two Brazilian referral centers.

Materials And Methods: Electronic searches were conducted across six databases, supplemented by manual searches and gray literature.

Volatile sulfur compounds and salivary parameters in patients undergoing head and neck cancer treatment: A preliminary study.

Background: Treatment for head and neck squamous cell carcinoma (HNSCC) is often associated with various adverse effects, including changes in salivary parameters and complaints of halitosis. This study aimed to investigate changes in volatile sulfur compound (VSC) levels and salivary parameters in patients undergoing treatment for HNSCC.

Methods: This prospective longitudinal study was conducted at a Brazilian oncology center, where a convenience sample of 24 HNSCC patients undergoing radiotherapy or chemoradiotherapy were evaluated for VSC levels, salivary flow, pH, viscosity, dry mouth, and tongue coating.

Diterpenes: An Updated Review Concerning Their Structural Diversity, Therapeutic Performance, and Future Pharmaceutical Applications.

The family is a rich source of bioactive terpenoids. Among its genera, is a conspicuous producer of diterpenes and includes approximately 175 species, many of which have medicinal uses. To date, 140 diterpenes from (JTDs) have been reported.

Morphological features and genetic background in ectomesenchymal chondromyxoid tumor: A systematic review.

Background: Ectomesenchymal chondromyxoid tumor (EMCMT) is a rare neoplasm that mainly affects the tongue and harbors recurrent, although not exclusive, gene fusions. Owing to its rarity, overlapping features with other tumors may lead to challenges in the microscopic diagnosis. We aimed to perform a systematic review focusing on the histomolecular findings of EMCMT of the oral and maxillofacial region and to evaluate the possible association between microscopic features with the genetic background.

Tooth loss from the perspective of studies employing a life course approach: a systematic review.

The life course approach scrutinizes factors that shape the development of diseases over time. Tooth loss, which is influenced by social, behavioral and biological factors, can occur at various stages of life and tends to become more prevalent in later years. This systematic review examined the influence of socioeconomic, psychosocial, biological and behavioral adversities in life on the likelihood of tooth loss.

Monnieriside A from promotes antinociceptive effects in models of inflammatory and postoperative pain in male mice.

Monnieriside A (MoA) is a chromone isolated from . This study investigated the antinociceptive potential of MoA in mice. MoA (0.

Volatile sulfur compounds, biofilm, and salivary parameters in patients with periodontal disease: a cross-sectional study.

This cross-sectional study aimed to evaluate the interplay between volatile sulfur compounds (VSC), biofilm, salivary parameters, and periodontal status in patients with and without periodontal disease. Sixty-four subjects diagnosed with periodontitis and 60 periodontally healthy individuals were included. Probing depth, clinical attachment level, bleeding on probing, tongue coating index, plaque index, number of teeth, spinnability of unstimulated whole saliva, and salivary flow rate were evaluated.

Immunohistochemistry and RT-PCR as ancillary tools in the diagnosis of acquired oral syphilis.

Objective: To investigate Treponema pallidum detection using immunohistochemistry (IHC) and reverse transcription-polymerase chain reaction (RT-PCR) assays in acquired oral syphilis (AOS).

Materials And Methods: Thirty-seven paraffin-embedded tissue specimens of AOS (32 secondary and five primary) were analyzed, integrating double-positive serological results with clinicodemographic and histopathological data. T.

Top 100 most-cited papers on diabetes mellitus in Dentistry: a bibliometric study.

This study assessed the features of the 100 most-cited papers on diabetes mellitus (DM) in dentistry using bibliometric measures. A search of the most cited papers on DM using journals included in the category "Dentistry, Oral Surgery and Medicine" in the Web of Science database up to January 2023 was performed. The complete bibliographic records of the selected papers were exported in plain text or Research Information Systems (RIS) file format.

Oral leukoplakia and erythroplakia in young patients: a southern Brazilian multicenter study.

The objective of the present study was to investigate the frequency of oral leukoplakia and oral erythroplakia among young patients from three Brazilian reference centers in Oral and Maxillofacial Pathology. A retrospective study was carried out from 2011 to 2021 on 861 patients diagnosed with oral leukoplakia and oral erythroplakia. Demographic and clinicopathological data were evaluated.

Factors associated with the anxiety score of deaf and hearing mothers.

Purpose: To associate maternal anxiety with sociodemographic factors, breastfeeding practices, oral habits, and the child's entry into daycare among deaf and hearing (non-deaf) mothers.

Methods: This retrospective comparative cross-sectional study included 116 mothers (29 deaf and 87 hearing) of children aged between two and five years. Deaf mothers belonged to a reference center in the city, while hearing mothers were contacted in public daycares where their children were enrolled.

Oral health-related quality of life in Fanconi anemia: a cross-sectional study.

Purpose: To evaluate the oral health-related quality of life (OHRQoL) of individuals diagnosed with Fanconi anemia (FA).

Methods: A cross-sectional study was conducted with FA patients from two Brazilian referral centers. Participants underwent a complete dental, periodontal, and oral mucosa examination, as well as assessment of resting salivary flow.

Comprehensive assessment of periodontal health in cerebral palsy: A systematic review and meta-analysis.

Aims: Cerebral palsy (CP) is the term for a set of neurological disorders resulting from brain damage that impairs motor function. The aim of the present study was to perform a systematic review of the literature to determine whether individuals with CP are at a greater risk of negative periodontal health outcomes compared to those without CP.

Methods: This study followed the recommendations of the MOOSE guidelines.

Effectiveness of antimicrobial photodynamic therapy in the treatment of peri-implantitis: systematic review and meta-analysis.

The purpose of this study was to evaluate the current scientific evidence on the effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjunctive treatment to mechanical debridement in the treatment of peri-implantitis. The Preferred Reporting Items for Systematic Reviews and Meta-analyses was followed. A protocol was registered in the International Prospective Registry of Systematic Reviews (PROSPERO #CRD42022361684).

Top 100 most-cited scientific articles in regenerative endodontics 2019-2023: A bibliometric analysis.

Background: Bibliometric analysis is a critical indicator of the influence and relevance of scientific papers, whilst also highlighting key contributors and gaps in knowledge in a scientific field.

Objectives: To update and analyse the 100 most-cited papers in regenerative endodontics from 2019 to 2023.

Methods: A search of the most-cited recent papers focusing on regenerative endodontics using journals included in the category, 'Dentistry, Oral Surgery & Medicine', in the Clarivate Web of Science database from 2019 to 2023 was performed.

Influence of Major Polyphenols on the Anti- Activity of Leaves: Isolation, LC-ESI-HRMS/MS Characterization and In Vitro Evaluation.

The content of chemical constituents in leaf extracts correlates positively with biological activities. The experimental objective was to carry out the phytochemical screening and purification of the major polyphenols from the leaves of . In addition, the anti- activity of the hydroalcoholic extract, fraction, subfractions and polyphenols purified were evaluated.