Publications by authors named "Luca Volpi"

Article Synopsis
  • Sinonasal malignancies that invade the orbit have poor prognoses, but a new surgical approach called extended-orbital exenteration (EOE) shows promise in improving outcomes.
  • * A study conducted across three institutions involved 48 orbital dissections and utilized a questionnaire to assess the procedure's feasibility and safety, with feedback from 25 surgeons.
  • * The findings indicate that while endoscopic-EOE is challenging, it is a feasible procedure that needs further clinical validation to evaluate its effectiveness in real-life situations.
View Article and Find Full Text PDF

Juvenile nasopharyngeal angiofibroma (JNA) is a benign tumor of the nasal cavity that predominantly affects young boys. Surgical removal remains the gold standard for the management of this disease. Preoperative intra-arterial embolization (PIAE) is useful for reductions in intraoperative blood loss and surgical complications.

View Article and Find Full Text PDF

Objectives/hypothesis: Maxillary cancers are rare and aggressive tumors, which can spread beyond the sinus bony walls. Preoperative assessment of infiltration of maxillary sinus floor (MSF) is paramount for surgical planning, as palatomaxillary demolition significantly impacts patients' quality of life. This study investigates the challenges involved in the preoperative and intraoperative evaluation of MSF infiltration and analyzes its prognostic relevance.

View Article and Find Full Text PDF

Background: Nasoseptal perforation repair is a challenging condition with no standard technique for repair recognized.

Methods: A case series of consecutive patients who underwent nasoseptal perforation repair with an anterior ethmoidal artery flap was conducted. Demographic data, preoperative features of the perforation and postoperative outcomes were analyzed.

View Article and Find Full Text PDF

Background: The Covid-19 pandemic has had a profound impact on the Otolaryngology outpatient clinical practice, which is at high risk of respiratory viral transmission due to the close contact between the examiner and the patient's airway secretions [1]. Moreover, most otolaryngological procedures, including oropharyngoscopy, generate droplets or aerosols from high viral shedding areas [1]. Thus, only non-deferrable consultations were performed in the outbreak's acute phase.

View Article and Find Full Text PDF

Objective/hypothesis: This study describes a multicentric experience with the use of prelacrimal approach (PLA), focusing on preoperative radiological parameters potentially associated with surgical outcomes and postoperative morbidity.

Study Design: Retrospective case-series.

Methods: A retrospective review of patients undergoing PLA in three European referral centers was performed.

View Article and Find Full Text PDF

Objectives/hypothesis: Although the Hadad-Bassagusteguy flap represents the first choice for middle and posterior skull base reconstruction and coverage of exposed bony areas, in some cases it is unavailable. The aim of this study is to describe, as an alternative option in selected cases, a modified posterior pedicle middle turbinate flap (mPPMTF) extended to the lacrimal area. Anatomical features, step-by-step harvesting technique, and surgical applications are presented.

View Article and Find Full Text PDF

Reconstruction of wide skull base defects resulting from multimodal treatment of cranial base malignancies are challenging. Endonasal pedicled flaps (e.g.

View Article and Find Full Text PDF

Objectives: Spontaneous cerebrospinal fluid (CSF) leaks are a rare but insidious clinical entity. In the recent literature, their pathogenesis has been linked with idiopathic intracranial hypertension (IIH). Considering a worse surgical outcome compared to traumatic leaks, a medical treatment of the underlying IIH has been suggested in order to prevent relapses.

View Article and Find Full Text PDF

Background: Italy was the first European country suffering from COVID-19. Health care resources were redirected to manage the pandemic. We present our initial experience with the management of urgent and nondeferrable surgeries for sinus and skull base diseases during the COVID-19 pandemic.

View Article and Find Full Text PDF

Background: Post therapeutic surveillance of head and neck neoplasms is a still debated issue in the current literature: although different works tried to establish frequency, modality, and efficacy of a routine follow-up, little evidence has been produced, in particular considering only sinonasal malignancies.

Methods: A retrospective review of patients treated for sinonasal malignancies in a single tertiary center and followed through a regular program of follow-up was carried out. Rate of recurrence, location, timing, diagnosis, and salvage treatment were the main data analyzed.

View Article and Find Full Text PDF

Background: Cryoprobe devices are used by ophthalmic and orbital surgeons for extraction of fluid-filled intraorbital lesions. No series has described cryodissection via an exclusively transnasal approach. We describe 2 cases of purely endoscopic transnasal removal of intraconal orbital hemangiomas with the aid of a dedicated cryoprobe.

View Article and Find Full Text PDF

Objectives: Adenoid cystic carcinoma (ACC) is a locally aggressive salivary gland malignancy prone to perineural invasion and local recurrences. In the literature, few data exist to guide treatment when this tumor involves the paranasal sinuses and skull base. We report our experience in the management of sinonasal adenoid cystic carcinoma through an endoscopic endonasal approach.

View Article and Find Full Text PDF

Objective: To analyze outcomes and prognostic factors of sinonasal nonsalivary non-intestinal-type adenocarcinoma (n-ITAC.) METHODS: A retrospective review of 22 consecutive patients with n-ITAC was performed.

Results: Average follow-up time was 77 months.

View Article and Find Full Text PDF

Background: The purpose of this study was to report the outcomes of endoscopic transnasal resection for sinonasal and anterior skull-base cancers in elderly patients.

Methods: A retrospective review was performed. The patients were divided into 2 groups, <70 years old and ≥70 years old and compared by univariate analysis.

View Article and Find Full Text PDF

Craniopharyngiomas are benign but aggressive epithelial tumors usually originating in the anterior lobe of the pituitary gland from squamous remnants of an incompletely involuted craniopharingeal duct developing from the Rathke pouch. To the authors' knowledge only 1 patient of a primary isolated ethmoidal craniopharyngioma has been reported in the literature.The authors report the case of a 17-year-old boy with a primary extracranial ethmoidal craniopharyngioma.

View Article and Find Full Text PDF

Background: Sinonasal inverted papillomas (IPs) can be associated synchronously or metachronously to invasive squamous cell carcinoma (SCC) in 5% to 10% of cases. The purposes of the present study were to analyze the outcomes of patients with sinonasal SCC arising from inverted papilloma (IP-SCC) treated through an endoscopic approach and review the pertinent literature.

Methods: The medical records of all patients treated for IP-SCC between 1997 and 2014 at 2 referral centers following a uniform policy were retrospectively analyzed.

View Article and Find Full Text PDF

The extra-skeletal form is an unusual type of Ewing sarcoma (ES) arising from soft tissue and in the literature there are reports of less than 50 patients describing the tumor in the paranasal sinuses and skull base. The histological diagnosis is crucial to plan the correct treatment and the molecular confirmation is mandatory in equivocal patients. A multimodality treatment with chemotherapy, surgery and radiotherapy improved the outcomes of these diseases during the last decades and a free-margin resection with the endoscopic transnasal technique is one of the most recent ways to manage these pathologies in selected patients, reducing the morbidities of the external approaches and preserving the quality of life of the patient.

View Article and Find Full Text PDF

Background: The management of frontal sinus disease still remains a challenging issue for rhinologists. Although endoscopic frontal sinus surgery has significantly advanced over the past years, there are some conditions in which the external approaches are still necessary. Recently, the increasing experience in endoscopic sinus surgery together with important technologic advancements have allowed expansion of the indications for selected lesions localized more and more lateral into the frontal sinus.

View Article and Find Full Text PDF
Article Synopsis
  • Olfactory neuroblastoma is a rare tumor that forms in a specific part of the nasal cavity, making it difficult to study and understand due to the challenges in growing its cells in lab settings.
  • Recent research using advanced molecular methods has provided insights into these tumors through a study involving 11 samples from 10 patients, highlighting a lot of variability in genetic changes among different tumors.
  • While some similarities with past literature were noted, such as the gain of chromosome 19 and specific segment changes, many findings did not confirm previous data, indicating a unique and complex genetic profile for these tumors.
View Article and Find Full Text PDF

Objective: To investigate different treatment strategies for primary early-stage (pT1-T2) sinonasal adenocarcinomas.

Methods: Retrospective case-control study. From 2000 to 2011, 61 cases were radically resected using an endoscopic endonasal approach.

View Article and Find Full Text PDF

Introduction: Dermoids of the Eustachian tube are rare benign developmental tumours that typically occur in female children. General consensus of classification and nomenclature has still not been reached. The treatment of choice consists of a radical surgical excision.

View Article and Find Full Text PDF