Publications by authors named "Luca Sartore"
In-stent restenosis (ISR) remains the predominant cause of stent failure and the most common indication for repeat revascularization. Despite technological advances in stent design, ISR continues to pose significant challenges, contributing to increased morbidity and mortality among patients undergoing percutaneous coronary interventions. In the last decade, intravascular imaging has emerged as an important method for identifying the mechanisms behind ISR and guiding its treatment.
View Article and Find Full Text PDFCardiovascular (CV) diseases caused 20.5 million deaths in 2021, making up nearly one-third of global mortality. This highlights the need for practical prognostic markers to better classify patients and guide treatment, especially in ischemic heart disease (IHD), which represents one of the leading causes of CV mortality.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers used a Bayesian multi-trait approach to analyze 10 cardiac traits from a large group of individuals and found significant genetic variants linked to heart function.
- * They identified three new variants in the genes RGS3, CHD3, and MRPL38 that affect various cardiac traits, with RGS3 showing a notable impact on multiple heart measurements and its role in inhibiting TGF-beta signaling related to heart issues.