Publications by authors named "Luca Salvatore De Santo"

The incidence, risk factors and prognostic implications of acute kidney injury (AKI) in patients undergoing redo cardiac surgery are still poorly defined. We prospectively collected data on 394 consecutive redo patients between January 2011 and October 2020. Patients were divided into groups according to the occurrence of different degrees of postoperative AKI (No AKI vs.

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Article Synopsis
  • The study examined the short- and long-term mortality rates of infective endocarditis (IE) among people who inject drugs (PWID) by analyzing data from hospitalized patients between 2000 and 2021.
  • Out of 485 IE patients, 55 (11%) were PWID, who were matched with 55 non-intravenous drug users (N-IDU) based on age and sex; PWID had higher rates of HCV co-infection and advanced liver disease.
  • Findings indicated that PWID faced a nearly threefold increased risk of long-term mortality after being hospitalized for IE compared to the N-IDU group, highlighting the need for further investigation into the factors contributing to their elevated mortality risk
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Objectives: Many Roman pontiffs are known to have had kidney stone disease. However, no specific report has explored the prevalence of the various stones in popes, which is the purpose of this study.

Materials And Methods: We extensively studied the histories of all popes (n = 264) from Saint Peter to John Paul II (34-2005).

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Objectives: This study was devised to investigate papal deaths due to acute kidney injury, a topic for which scarce data exist.

Materials And Methods: We studied all popes between John XXI, who died in 1277 of crush syndrome, and John Paul II, who died of anuria and urinary sepsis in 2005.

Results: Between pontification years from 1277 to 2005, 21 of 78 popes (26.

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Objectives: In this study, we aimed to investigate the effects of malaria on the lives of Roman pontiffs.

Materials And Methods: The histories of all 264 popes from Saint Peter to John Paul II were extensively studied.

Results: Malaria affected the lives of Roman pontiffs.

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Preoperative anemia has been associated with increased morbidity and mortality after cardiac surgery, but little is known about its prognostic value in the setting of redo procedure. A retrospective, observational cohort study of prospectively collected data was undertaken on 409 consecutive patients referred for redo cardiac procedures between January 2011 and December 2020. The EuroSCORE II calculated an average mortality risk of 25.

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The purpose of this study is to explore the historical background of edema as a prognostic sign in popes, a special category of medical subjects whose health status was closely monitored and chronicled because of their unique important status in the events of their times. Nine out of 51 popes, who reigned in the years 1555-1978, died edematous at a mean age of 75.5 years of age.

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Objectives: Healthcare systems worldwide have been overburdened by the coronavirus disease 2019 (COVID-19) outbreak. Accordingly, hospitals had to implement strategies to profoundly reshape both non-COVID-19 medical care and surgical activities. Knowledge about the impact of the COVID-19 pandemic on cardiac surgery practice is pivotal.

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Background: Health systems worldwide have been overburdened by the "COVID-19 surge". Consequently, strategies to remodulate non-COVID medical and surgical care had to be developed. Knowledge of the impact of COVID surge on cardiac surgery practice is mainstem.

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Deep sternal wound infections (DSWI), although an infrequent complication, significantly impair postoperative outcomes after coronary artery bypass grafting (CABG) surgery. Among several preventive strategies, topical antibiotic therapy immediately before sternal closure has been strongly advocated. In this retrospective analysis, the incidence of DSWI in 517 patients undergoing isolated CABG and receiving rifampicin irrigation of mediastinum, sternum and suprasternal tissues was compared to an historical consecutive cohort of 448 patients.

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Noninvasive ventilation (NIV) is an increasingly used method of respiratory support. The use of NIV is expanding over the time and if properly applied, it can save patients' lives and improve long-term prognosis. However, both knowledge and skills of its proper use as life support are paramount.

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In Italy in 2017 out of 2738 assessments of death, there was a 28.7% of oppositions of family members to the removal of organs post-mortem. This opposition is a serious limitation to the development of transplantation programs.

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A U-shaped relationship between body mass index (BMI) and outcomes emerged after cardiac surgery. This review analyses the physio pathologic basis of obesity related complications and evaluates prognostic implications. Both leaner and morbid obese should be considered pre-operatively rather than reactively and, when referred for elective surgery, should undergo a focused metabolic status management, and a thorough evaluation of health status.

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Thromboembolic complications after cardiac valve replacement are due to a complex interplay between patients' characteristics, device features and anticoagulation intensity. Subtle design and material differences in available prostheses may thrombosis. We conducted a post-hoc sub-analysis of the LOWERING-IT database to test the safety and feasibility of a low-level oral anticoagulant regime in low-risk patients with aortic LivaNova prosthetic valve replacement.

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Background: Red blood cell (RBC) transfusion is a well-known predictor of acute kidney injury (AKI) and death after cardiac surgery. This study aimed to define the relationship between age and the need for RBC.

Methods: Study population included 1,765 consecutive patients undergoing on-pump procedures from 2013 to 2015.

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Unlabelled: Introduction Maximum time-to-rescue has been studied accurately for many earthquakes in the years 1985-2004. No study is available for historical quakes. Hypothesis/Problem This study aimed to evaluate long-term survivors (from the fifth day after the quake) of the Messina-Reggio Calabria earthquake (1908; Italy), which is considered, historically, to be the worst seismic event in Europe.

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