Publications by authors named "Luca Roasio"

Article Synopsis
  • The study investigates meningitis-retention syndrome (MRS), focusing on its clinical and radiological features, treatment options, and urinary outcomes to better understand the syndrome and the role of corticosteroids.
  • A new case of MRS was presented alongside a review of 28 previous cases, revealing that MRS typically occurs with aseptic meningitis and urinary retention, with a mean interval of about 6.4 days between symptoms.
  • Findings suggest MRS is self-limited, often without pathological findings on neurophysiological studies, and corticosteroids, antibiotics, and antivirals have not shown effectiveness in altering the syndrome's course.
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Article Synopsis
  • The study analyzed RSV infections in children under 3 years old in 15 Pediatric Emergency Departments across different years (2019, 2020, 2021) to understand the impact of COVID-19 restrictions.
  • There was a significant increase in RSV cases in 2021 compared to 2019 and 2020, particularly among 2-3 year-olds, with the peak occurrence happening a month earlier in 2021.
  • Despite the increase in RSV admissions in 2021, the severity of the infections remained consistent across all years studied, indicating a shift in the age demographic affected by RSV post-COVID-19.
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Background: COVID-19 pandemic caused huge decrease of pediatric admissions to Emergency Department (ED), arising concerns about possible delays in diagnosis and treatment of severe disorders.

Methods: Impact of COVID-19 on Pediatric Emergency Room (ICOPER) was a retrospective multicentre observational study including 23 Italian EDs.All the children <18 years admitted, between March 9th and May 3rd 2020 stratified by age, priority code, cause of admission and outcome have been included and compared to those admitted in the same period of 2019.

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Objectives: Early blood phenylalanine (Phe) elevation after birth enables screening for and anticipation of the diagnosis of phenylketonuria. The differential impact of factors involved in this phenomenon, however, has not been elucidated. To solve this question, phenotype, genotype, dietary Phe intake, timing of blood collection, and Phe metabolism were retrospectively analyzed in 21 phenylketonuria newborns and prospectively in 1.

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