Publications by authors named "Luca Lusnig"

In the realm of liver transplantation, accurately determining hepatic steatosis levels is crucial. Recognizing the essential need for improved diagnostic precision, particularly for optimizing diagnosis time by swiftly handling easy-to-solve cases and allowing the expert time to focus on more complex cases, this study aims to develop cutting-edge algorithms that enhance the classification of liver biopsy images. Additionally, the challenge of maintaining data privacy arises when creating automated algorithmic solutions, as sharing patient data between hospitals is restricted, further complicating the development and validation process.

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Structure determination of filamentous molecular complexes involves the selection of filaments from cryo-EM micrographs. The automatic selection of helical specimens is particularly difficult, and thus many challenging samples with issues such as contamination or aggregation are still manually picked. Here, two approaches for selecting filamentous complexes are presented: one uses a trained deep neural network to identify the filaments and is integrated in SPHIRE-crYOLO, while the other, called SPHIRE-STRIPER, is based on a classical line-detection approach.

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Article Synopsis
  • A novel model called the Parzen neural network (PNN) is introduced for estimating multivariate probability density functions, aiming to improve on traditional methods.
  • The PNN is highlighted for its simplicity, unbiased modeling, and efficiency during testing, making it a strong candidate for practical applications.
  • The paper includes experiments on synthetic datasets and a challenging task involving sex determination from CT-scan images, with findings that also contribute to anthropological insights.
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Article Synopsis
  • * The study aimed to create standard criteria for analyzing skull-face relationships, involving 37 experts who evaluated 65 criteria across 24 superimpositions.
  • * Although strong associations were not found, the research provided key insights into standardization and introduced a new methodology based on morphological patterns.
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Sex determination on skeletal remains is one of the most important diagnosis in forensic cases and in demographic studies on ancient populations. Our purpose is to realize an automatic operator-independent method to determine the sex from the bone shape and to test an intelligent, automatic pattern recognition system in an anthropological domain. Our multiple-classifier system is based exclusively on the morphological variants of a curve that represents the sagittal profile of the calvarium, modeled via artificial neural networks, and yields an accuracy higher than 80 %.

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