Publications by authors named "Luca Lepri"
Article Synopsis
- The study investigates the use of buccal mucosa grafts (BMG) for surgical treatment of Peyronie's Disease (PD), emphasizing their effectiveness in reducing complications and promoting recovery.
- Conducted over six years, the research involved 27 patients who had significant curvature issues and were unresponsive to other treatments, with follow-up assessments including ultrasound and erectile function questionnaires.
- Results showed that BMG led to quick restoration of spontaneous erections and minimized the risk of erectile dysfunction, highlighting its role in successful surgical outcomes for PD.
Introduction And Objectives: PSA elevation is associated with prostate cancer and it is used in screening programs for its diagnosis. It is one of the most common indications for referral to an urologist. There's no consensus about what to do in PSA elevation management.
View Article and Find Full Text PDFLichen sclerosus (LS) is an inflammatory and chronic disease that causes itching, pain, dysuria, urinary retention, dyspareunia and sexual dysfunction, in both men and women. The first line pharmacological treatment is based on the use of topical steroids, which have proved their efficacy in 60-70% of cases but with a high rate of relapses in time (50-80% of the patients of both sexes). The purpose of our non-randomised prospective pilot study was to evaluate the efficacy and tolerability of a new loco regional therapy with polydeoxyribonucleotides (PDRN) in the treatment of male genital LS.
View Article and Find Full Text PDFThis prospective study assesses the impact of high-intensity focused ultrasound (HIFU) on lower urinary tract by comparing pre- and postoperative symptoms and urodynamic changes. Thirty consecutive patients with clinically organ-confined prostate cancer underwent urodynamic study before HIFU and then at 3-6 months after surgery. Continence status and symptoms were analyzed by means of International Prostate Symptoms Score IPSS and International Index Erectile Function IIEF5.
View Article and Find Full Text PDFIntroduction: Radical prostatectomy (RP) in patients with high-risk prostate cancer (PC) [prostate specific antigen (PSA) ≥ 20 ng/mL, and/or Gleason score ≥ 8, and/or cT3a disease] is considered an optional therapy, usually as a part of multimodal approach. Aim of the study is to evaluate the outcome of radical prostatectomy in case of specimen-confined (SC) disease and to compare it with patients with pathological locally-advanced disease.
Materials And Methods: Data from 176 consecutive patients with high-risk prostate cancer who underwent RP as initial therapy were analyzed, identifying subjects with specimen-confined disease (i.