Publications by authors named "Luca Jannik Braunger"
J Parkinsons Dis
July 2024
Article Synopsis
- Mutations in the LRRK2 gene are linked to both sporadic and familial Parkinson's disease, and while new therapies are beginning clinical trials, it's difficult to determine which patients will benefit the most.
- This study explores the potential of measuring specific microRNA (miRNA) profiles in blood and cerebrospinal fluid to distinguish between patients with LRRK2 mutations and those with sporadic forms of the disease.
- Results show that certain miRNAs, particularly miR-29c-3p, can effectively differentiate between these groups with high accuracy, suggesting that tracking these biomarkers could help evaluate the effectiveness of LRRK2-targeted treatments in the future, though further research with larger groups is needed.
