Publications by authors named "Luca Egger"
High free-volume copolymers were prepared via polycondensation with 2,3,5,6,-tetrafluoroterephthalonitrile (TFTPN) in which a portion of the 3,3,3',3'-tetramethyl-1,1'-spirobisindane (TTSBI) of PIM-1 was replaced with dibutyl anthracene maleimide (4bIII). An investigation of free volume using positron annihilation lifetime spectroscopy (PALS), and gas permeation measurements was carried out for the thin film composite copolymer membranes and compared to PIM-1. The average free volume hole size and the gas permeance of the copolymer membranes increased with decreasing TTSBI content in the copolymer.
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- The study analyzes mortality rates among patients who started combination antiretroviral therapy (ART) after experiencing AIDS-defining events (ADEs) to determine how different ADEs impact patient outcomes.
- A significant sample of 31,620 patients with no prior ADEs was examined, and results showed that 2880 ADEs were diagnosed; mortality was particularly high for non-Hodgkin's lymphoma and progressive multifocal leukoencephalopathy.
- The findings categorize ADEs into three groups based on their mortality risk: severe (e.g., non-Hodgkin's lymphoma), moderate (e.g., cryptococcosis), and mild (other ADEs), highlighting the varying levels of risk associated with different conditions following ART initiation.
Objective: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-naïve patients initiating ART.
Design: Observational cohort study of patients initiating ART between January 2000 and December 2005.
Setting: The Antiretroviral Therapy Cohort Collaboration (ART-CC) is a collaboration of 15 HIV cohort studies from Canada, Europe, and the United States.