Publications by authors named "Luca Bremner"
Article Synopsis
- The study evaluates the recovery of cardiac diagnostic procedures in Italy one year after the COVID-19 outbreak, focusing on procedure volumes, practices, and staff well-being.
- A global survey revealed a 72% drop in cardiac diagnostic procedures in April 2020 compared to March 2019, with only a slight recovery (3% increase) by April 2021, though some specific tests showed increased volumes.
- Many healthcare centers adopted measures like physical distancing and COVID-19 screening, but 25% of physicians reported high psychological stress levels, highlighting ongoing challenges within the healthcare system.
Article Synopsis
- This study focused on how Body Mass Index (BMI) influences radiation exposure in patients with chest pain undergoing different imaging techniques, highlighting the importance of optimizing doses for patient safety.
- A total of 9,046 patients were analyzed, and results showed PET/CT had the lowest radiation exposure, particularly for patients with higher BMI, while CCTA had significantly higher doses in heavier patients.
- The findings emphasize that while radiation doses for these imaging methods are generally modest, understanding BMI's impact is crucial for improving imaging practices and reducing unnecessary radiation exposure.
Article Synopsis
- - The COVID-19 pandemic significantly disrupted cardiovascular testing in Latin America (LATAM), with a study finding a 21% decrease in procedure volumes from pre-pandemic levels in April 2021, contrasting with zero change in the rest of the world.
- - Central America and Mexico experienced the largest reductions in procedures (47%), while healthcare centers in LATAM reported more staff layoffs and salary cuts than those in other regions.
- - The study highlighted the lasting effects of the pandemic on cardiovascular care and emphasized the need for mental health support for healthcare workers in LATAM, as nearly 50% reported excessive psychological stress.
Group A (GAS) infections can cause neuropsychiatric sequelae in children due to post-infectious encephalitis. Multiple GAS infections induce migration of Th17 lymphocytes from the nose into the brain, which are critical for microglial activation, blood-brain barrier (BBB) and neural circuit impairment in a mouse disease model. How endothelial cells (ECs) and microglia respond to GAS infections, and which Th17-derived cytokines are essential for these responses are unknown.
View Article and Find Full Text PDFThe ease with which the unicellular yeast can be manipulated genetically and biochemically has established this organism as a good model for the study of human mitochondrial diseases. The combined use of biochemical and molecular genetic tools has been instrumental in elucidating the functions of numerous yeast nuclear gene products with human homologs that affect a large number of metabolic and biological processes, including those housed in mitochondria. These include structural and catalytic subunits of enzymes and protein factors that impinge on the biogenesis of the respiratory chain.
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