Publications by authors named "Luca Baroni"
This study aimed to analyze Optical Coherence Tomography (OCT) parameters and Macular Pigment Optical Density (MPOD) changes in patients affected by Retinitis pigmentosa (RP). Eighteen eyes of 18 patients suffering from early-stage RP were enrolled in our observational study. 18 eyes of 18 patients age and gender matched were enrolled as controls.
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- Single-photon optogenetics is a powerful technique in neuroscience that allows for precise control of specific types of neurons, making it valuable for studying and interfacing with brain circuits.
- Advances like miniaturized implantable stimulator arrays enable researchers to examine brain activity over long periods, potentially aiding in restoring sensory and motor functions.
- Despite its benefits, achieving selective activation within cortices is complicated due to neuron shape influencing optogenetic responses; however, optimizing optical setups could enhance stimulation precision more effectively than genetic targeting alone.
Vision is fundamentally context-dependent, with neuronal responses influenced not just by local features but also by surrounding contextual information. In the visual cortex, studies using simple grating stimuli indicate that congruent stimuli - where the center and surround share the same orientation - are more inhibitory than when orientations are orthogonal, potentially serving redundancy reduction and predictive coding. Understanding these center-surround interactions in relation to natural image statistics is challenging due to the high dimensionality of the stimulus space, yet crucial for deciphering the neuronal code of real-world sensory processing.
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- The study evaluated the effectiveness of contrast-enhanced CT (CECT) compared to unenhanced CT (UECT) in staging and assessing treatment response for F-FDG-avid lymphomas using a 64-slice PET/CT scanner.
- While CECT identified a few additional lesions and had some agreement with PET results, the overall added diagnostic value was below the clinically significant threshold, with no significant difference in accuracy between UECT and CECT.
- The findings suggest that CECT may not be necessary for staging and treatment assessment of F-FDG-avid lymphomas, potentially reducing radiation exposure and risks associated with contrast use.