Publications by authors named "Luca Aldo Edoardo Vago"
Article Synopsis
- - The study investigates how the HLA class I genotype influences the size of the HIV viral reservoir in individuals on antiretroviral therapy (ART), highlighting the significant roles of HLA-B and -C genes in this process.
- - Using advanced bioinformatic tools, the researchers assessed the relationship between HLA alleles and HIV antigen presentation, finding that certain HLA types, like HLA-B*57:01 and HLA-B*58:01, may enhance immune responses against HIV.
- - The research suggests a potential interaction between specific HLA-peptide complexes and factors like the CCR5 ∆32 mutation in regulating HIV replication and controlling the size of the viral reservoir, proposing a multifaceted approach to understanding HIV management
