Publications by authors named "Luc Souverain"
Article Synopsis
- Dandruff is a persistent scalp condition that can be influenced by various environmental and personal factors, leading to changes in scalp health that may require treatment like Selenium disulfide (SeS2) shampoo.
- Research focused on how SeS2 shampoo affects dandruff severity, scalp microbiome, and sebum properties during treatment and after resuming normal conditions.
- The study found that SeS2 significantly reduced dandruff symptoms and harmful microbes in the scalp, improved the balance of beneficial bacteria, and enhanced the quality of scalp oils, showing good tolerance from users even after stopping treatment.
Background: In vivo multiphoton imaging and automatic 3D image processing tools provide quantitative information on human skin constituents. These multiphoton-based tools allowed evidencing retinoids epidermal effects in the occlusive patch test protocol developed for antiaging products screening. This study aimed at investigating their relevance for non-invasive, time course assessment of retinoids cutaneous effects under real-life conditions for one year.
View Article and Find Full Text PDFRepeated nonextreme sun exposures induce skin pigmentation by increasing melanin production and by oxidizing preexisting melanin and melanin precursors. This leads to skin disorders and skin color heterogeneity such as hyperpigmented spots. We assessed 31 randomized, controlled clinical trials to determine the potential of vitamin C to limit ultraviolet (UV) daylight-induced pigmentation, considering dose response and different skin type populations (Caucasian and Chinese).
View Article and Find Full Text PDFComparison of Healthy and Dandruff Scalp Microbiome Reveals the Role of Commensals in Scalp Health.
Front Cell Infect Microbiol
September 2019
Article Synopsis
- Studies on the scalp microbiome among diverse populations show a link between dandruff and imbalances in bacteria and fungi, though the exact role of these microorganisms in scalp health is still not well understood.
- Research involving 140 Indian women identified specific bacterial species associated with healthy scalps and dandruff, revealing a unique connection with previously uncharacterized fungal species in dandruff cases.
- The findings suggest that scalp bacteria may play a crucial role in maintaining nutrient balance, underscoring the importance of the scalp microbiome in understanding dandruff's underlying causes, similar to what has been observed with the gut microbiome.
Article Synopsis
- - Dandruff is influenced by three main factors: personal susceptibility, scalp oil (sebum), and Malassezia yeast, with a study focusing on the role of sebum in dandruff development.
- - An analysis showed that squalene, a key component of scalp oil, is significantly more oxidized in individuals with dandruff, indicating higher levels of oxidative stress compared to those without dandruff.
- - The study suggests that the increased levels of oxidized squalene (SQOOH) might contribute to dandruff by compromising scalp barrier function and possibly serving as an inflammatory factor, with Malassezia being a possible contributor to this process.