[Ameloblastic carcinoma: primary or secondary?].

Ameloblastic carcinoma is a rare neoplasm. It can arise de novo or in a preexisting benign ameloblastoma. Most cases arise in older patients.

Clinical outcome in patients with locally advanced bladder carcinoma treated with conservative multimodality therapy.

Objectives: To describe the outcome of patients with muscle-invasive bladder carcinoma treated with multimodality therapy in our institution from 1993 to 2002.

Methods: The charts of 60 patients with Stage T2-T4N0-N1M0 treated with transurethral resection of bladder tumor followed by a chemoradiotherapy combination were retrospectively reviewed. Of the 60 patients, 22 had received neoadjuvant chemotherapy (methotrexate, cisplatin, and vinblastine or methotrexate, adriamycin, cisplatin, and vinblastine) followed by concomitant chemoradiotherapy (weekly cisplatin/carboplatin or a cisplatin and 5-fluorouracil combination), and 38 had received concomitant chemoradiotherapy alone.