Background: We assessed the efficacy of artemisinin-based combination therapies for treatment of uncomplicated malaria, with or without co-infecting spp., in Sumatera, Indonesia.
Methods: Febrile patients aged >6 months with uncomplicated were randomized to receive dihydroartemisinin-piperaquine or artemether-lumefantrine, plus single-dose primaquine, and were followed for 42 days.
Artemisinin-based combination therapy (ACT) is the first-line antimalarial regimen in Indonesia. Susceptibility of to artemisinin is falling in the Greater Mekong subregion, but it is not known whether the efficacy of current combinations is also threatened in nearby Sumatera. We evaluated the genetic loci , and , considered to be under selection by artemisinin combination therapy, among 404 infections identified by PCR detection in a cross-sectional survey of 3,731 residents of three regencies.
View Article and Find Full Text PDFBackground: As Indonesia works toward the goal of malaria elimination, information is lacking on malaria epidemiology from some western provinces. As a basis for studies of antimalarial efficacy, we set out to survey parasite carriage in 3 communities in North Sumatera Province.
Methods: A combination of active and passive detection of infection was carried out among communities in Batubara, Langkat, and South Nias regencies.
A retrospective study was done during 1984-1988 in the pediatric ward of Dr. Pirngadi Hospital revealing 41 cases of acute hepatitis, consisted of 61.0% boys and 39.
View Article and Find Full Text PDFFrom July to August 1988, a cross sectional analytical study on factors influencing bottle-feeding practice in infants at the Well-Child Clinic Dr. Pirngadi Hospital Medan, was conducted by using a designated interview and questionnaire. The sample size was determined by a standard formula.
View Article and Find Full Text PDFBetween May and July 1985, a cross-sectional study on hepatitis B virus (HBV) infection and hepatitis B virus carrier state was conducted in children at two locations of Mobil Oil Indonesia i.e. Jakarta and Medan.
View Article and Find Full Text PDFA retrospective study on an immunization programme was carried out in the Well Baby Clinic, Child Health Department, School of Medicine, University of North Sumatera, Dr. Pirngadi Hospital, Medan from January to December 1986. Of the 5951 total visits (an average of 495 visits each month) 3960 were primary and 1991 secondary visits.
View Article and Find Full Text PDFPaediatr Indones
November 1989
During the period of 3 months (February-April 1987), a prospective study on oxyuariasis among children had been conducted at Child Health Department of Dr. Pirngadi Hospital Medan. All children over 8 months of age were included in this study.
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