Ephrin-A2 promotes prostate cancer metastasis by enhancing angiogenesis and promoting EMT.

Background: Ephrin-A2, a member of the Eph receptor subgroup, is used in diagnosing and determining the prognosis of prostate cancer. However, the role of ephrin-A2 in prostate cancer is remains elusive.

Methods: We established stable clones overexpressing or silencing ephrin-A2 from prostate cancer cells.

Dry Rolling/Sliding Wear of Bainitic Rail Steels under Different Contact Stresses and Slip Ratios.

This study aims to deeply understand the effect of contact stress and slip ratio on wear performances of bainitic rail steels. The results showed that the wear loss increased as the contact stress and slip ratio increased. Based on the surface damage morphology and microstructural analyses, it revealed that the rolling contact fatigue wear mechanism played a significant role under the low slip ratio, but the dominant wear mechanism transferred to the abrasive wear at the high slip ratio.