Publications by authors named "Lubin Gou"
Introduction: The associations between gray matter (GM) change and neurotransmitter systems in hepatitis B virus-related cirrhosis (HBV-RC) are still poorly understood.
Methods: We recruited 60 HBV-RC patients and 60 healthy controls (HCs). Difference of GM volume between HBV-RC and HC groups was evaluated at global and voxel levels.
Article Synopsis
- - The study investigated MRI features to identify and differentiate the morphological and functional abnormalities associated with Parkinson's disease (PD) compared to normal aging changes in healthy individuals.
- - Participants included 32 PD patients, 42 age-matched healthy controls (HCg1), and 33 younger controls (HCg2), with a focus on assessing cortical volume and brain connectivity.
- - Results showed reduced cortical volumes in the frontal lobe and temporal lobe for HCg1 compared to HCg2, while PD patients didn't have significant volume differences from HCg1 but displayed lower connectivity, highlighting distinct changes caused by PD versus age-related changes.
Article Synopsis
- A systematic review was conducted to evaluate how effective machine learning (ML)-based radiomics is in predicting IDH mutations in glioma patients by analyzing articles from several major databases.
- The review included 14 studies with a total of 1,740 patients, revealing that ML had a high area under the curve (AUC) of 0.90, indicating strong diagnostic accuracy.
- Key factors influencing the diagnostic capability were found to include the modeling methods used, the grade of glioma, and whether the model integrated MRI and clinical data.
Purpose: We aimed to investigate the multilevel impairments of brain structural network in patients with minimal hepatic encephalopathy (MHE).
Methods: Twenty-two patients with MHE and 22 well-matched healthy controls (HC) underwent structural magnetic resonance imaging (MRI) brain scans and neuropsychological evaluations. Individual brain structural networks were constructed using diffusion tensor imaging.
Depression is common in Parkinson's disease (PD) and is correlated with the severity of motor deficits and quality of life. The present study aimed to investigate alterations in the structural brain network related to depression in Parkinson's disease (d-PD) and their correlations with structural impairments of white matter (WM). Data were acquired from the Parkinson Progression Markers Initiative (PPMI) database.
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