Peritoneal dialysis is the better therapy choice for successful anti-hepatitis B vaccination.

Patients treated with renal replacement therapy (RRT) are considered to be at higher risk for infection with hepatitis B virus (HBV). Immunoprophylaxis is therefore deemed a standard of care. Active immunization in RRT patients leads to a lower incidence of protective titers of HBV antibodies (HBAbs) than the titers seen in healthy counterparts.