Publications by authors named "Luat Le"
The let-7 family of miRNAs have been shown to control developmental timing in organisms from C. elegans to humans; their function in several essential cell processes throughout development is also well conserved. Numerous studies have defined several steps of post-transcriptional regulation of let-7 production; from pri-miRNA through pre-miRNA, to the mature miRNA that targets endogenous mRNAs for degradation or translational inhibition.
View Article and Find Full Text PDFTick-borne encephalitis virus (TBEV) is a zoonotic agent that causes acute central nervous system (CNS) disease in humans. We previously suggested that immune response in addition to CNS infection contribute to mouse mortality following TBEV infection. However, we did not examine the influence of virus variants in the previous study.
View Article and Find Full Text PDFArticle Synopsis
- Echovirus 30 (E30) and Japanese encephalitis virus (JEV) are prevalent causes of acute meningitis in Southeast Asia, prompting a study to differentiate between them due to potential misdiagnosis, particularly during an outbreak in Vietnam (2001-2002).
- A retrospective study analyzed clinical records of 43 E30 and 60 JEV cases, comparing symptoms and clinical parameters using statistical methods.
- Results indicated that symptoms like fever, headache, and vomiting were common to both, but E30 cases showed a higher prevalence of headache and vomiting combinations, while JEV cases exhibited stronger neurological symptoms and distinct cerebrospinal fluid (CSF) profiles.