Publications by authors named "Luana Graziele Pereira Bezerra"
Synergistic effects of glial cell line-derived neurotrophic factor and base-medium on in vitro culture of testicular tissue derived from prepubertal collared peccary.
Andreia Maria da Silva Ana Glória Pereira Luana Graziele Pereira Bezerra Andreza Vieira Brasil Alexsandra Fernandes Pereira
Cell Biol Int
September 2024
Article Synopsis
- The study assessed how different culture media and concentrations of GDNF affect the in vitro culture of testicular tissues from prepubertal collared peccaries over 28 days.
- Using Dulbecco's modified essential medium (DMEM) and StemPro-34 SFM, researchers found that the StemPro medium with 10 ng/mL GDNF led to better morphology scores compared to DMEM.
- While cell viability remained consistent across treatments (~70%), only DMEM plus 10 ng/mL GDNF notably improved cellular proliferation by Days 14 and 28, indicating the importance of GDNF for cell survival and growth in cultured testicular tissue.