Diurnal variations in corneal biomechanics in healthy young adults.

Purpose: To assess the diurnal changes in corneal biomechanics in healthy young adults.

Methods: At Wenzhou Medical University Eye Hospital in China, a prospective case series. Each healthy subject had six Corvis ST examinations, from 10:00 on a first day to 6:00 on the following day, at 4-hour intervals.

Perceived Supervisor Support and Academic Procrastination in Postgraduate Students: Roles of Basic Psychological Needs Satisfaction and Learning Engagement.

Academic procrastination is a common problem among postgraduate students, one that has caused negative consequences that cannot be ignored. Therefore, finding out how to effectively eliminate academic procrastination behavior has become an essential task in educational practice. Based on the use of Self-Determination Theory (SDT) to explore the relationship between the perceived supervisor support and academic procrastination of postgraduate students, a total of 448 questionnaires were gathered from postgraduate students across China.

Research on improving the ranging accuracy of ships with stereo vision through Kalman filter optimization.

The real-time and accurate detection and ranging of ships play a pivotal role in ensuring navigation safety, this study aims to enhance the navigation safety and environmental perception capabilities of inland waterway vessels. In the ship detection stage, addressing challenges such as large parameters, high computational complexity, and poor real-time performance in existing ship detection models, this paper proposes the MS-YOLOv5s ship target detection algorithm. This algorithm, based on YOLOv5s, utilizes the lightweight MobileNetV3-Small network to replace the original YOLOv5s feature extraction backbone network, thereby improving the detection speed.

Electrochromic windows with fast response and wide dynamic range for visible-light modulation without traditional electrodes.

Electrochromic (EC) devices represent an emerging energy-saving technology, exhibiting the capability to dynamically modulate light and heat transmittance. Despite their promising potential, the commercialization of EC devices faces substantial impediments such as high cost, intricate fabrication process, and low optical contrast inherent in conventional EC materials relying on the ion insertion/extraction mechanism. In this study, we introduce an innovative "electrode-free" electrochromic (EC) device, termed the EECD, which lacks an EC-layer on the electrodes during device assembling and in the bleached state.

A Crystalline-Water Electrolyte Enabled High Depth-of-Discharge Anodes in Aqueous Zinc Metal Batteries.

Aqueous zinc metal batteries are regarded as a promising energy storage solution for a green and sustainable society in the future. However, the practical application of metallic zinc anode is plagued by the thermodynamic instability issue of water molecules in conventional electrolytes, which leads to severe dendrite growth and side reactions. In this work, an ultra-thin and high areal capacity metallic zinc anode is achieved by utilizing crystalline water with a stable stoichiometric ratio.

Optimization of offshore wind farm inspection paths based on K-means-GA.

As global demand for offshore wind energy continues to rise, the imperative to enhance the profitability of wind power projects and reduce their operational costs becomes increasingly urgent. This study proposes an innovative approach to optimize the inspection routes of offshore wind farms, which integrates the K-means clustering algorithm and genetic algorithm (GA). In this paper, the inspection route planning problem is formulated as a multiple traveling salesman problem (mTSP), and the advantages of the K-means clustering algorithm in distance similarity are utilized to effectively group the positions of wind turbines, thereby optimizing the inspection schedule for vessels.

Fraxetin ameliorates symptoms of dextran sulphate sodium-induced colitis in mice.

Ulcerative colitis (UC) is one of the primary inflammatory bowel diseases (IBDs) and causes a serious threat to human public health around the world. Currently, there are no proven safe and effective treatment options to treat UC. Fraxetin (Fxt) is a widely recognized antioxidant and anti-inflammatory legume derived from ash bark.

Network pharmacology-based exploration identified the antiviral efficacy of Quercetin isolated from mulberry leaves against enterovirus 71 via the NF-κB signaling pathway.

Mulberry leaf (ML) is known for its antibacterial and anti-inflammatory properties, historically documented in "Shen Nong's Materia Medica". This study aimed to investigate the effects of ML on enterovirus 71 (EV71) using network pharmacology, molecular docking, and experiments. We successfully pinpointed shared targets between mulberry leaves (ML) and the EV71 virus by leveraging online databases.

Multi-threshold image segmentation of 2D OTSU inland ships based on improved genetic algorithm.

Waterway transportation is a crucial mode of transportation, but ensuring navigational safety in waterways requires effective guidance of ships by the Water Resources Bureau. However, supervisors may only be interested in the ship portion of a complex image and need to quickly obtain relevant ship information. Therefore, this paper proposes a two-dimensional OTSU inland ships multi-threshold image segmentation algorithm based on the improved genetic algorithm.

Microglia play an important role in PRV infection-induced immune responses of the central nervous system.

Pseudorabies virus (PRV) can infect multiple hosts and lead to fatal encephalitis. There is a significant increase in the number of microglia in the brain of animals infected with PRV. However, whether and how microglia contribute to central nervous system damage in PRV infection remain unknown.

A Configurational Analysis of Small and Medium-Sized Enterprises' Radical Innovations: The Perspective of Dynamic Capabilities.

Adopting a configurational perspective, this study explored the pathways for small and medium-sized enterprises (SMEs) to achieve high levels of radical innovation. On the basis of dynamic capabilities theory, six causal conditions for radical innovation were identified at both external and internal levels-that is, environmental turbulence (i.e.

Correction: Interaction between laminin-5γ2 and integrin β1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins.

The original version of this Article contained an error in the author affiliations. Affiliation number 4 incorrectly read "Department of Gastroenterology and Hepatology, Tianjin Institute of Digestive Disease, Tianjin Institute of Digestive Disease". It should be "Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300052, China".

Interaction between laminin-5γ2 and integrin β1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins.

Colorectal cancer (CRC) is a common cancer type and a threat to human health. Tumor budding (TB) is the presence of a single cancer cell or clusters of up to five cancer cells prior to the invasive front of an aggressive carcinoma and is an independent prognosis factor for CRC. The molecular mechanism of TB is still unclear, and drugs that inhibit this process are still in the blank stage.

Selenium-lentinan inhibits tumor progression by regulating epithelial-mesenchymal transition.

Background: Selenium supplementation can be used to treat tumors. However, inorganic selenium is highly toxic, and natural organic selenium is extremely rare. Polysaccharides can improve drug bioavailability and targeting.

Protease-activated receptor-1 (PAR1) promotes epithelial-endothelial transition through Twist1 in hepatocellular carcinoma.

Background: Tumor cells transfer into endothelial cells by epithelial-endothelial transition (EET), which is characterized by vasculagenic mimicry (VM) in morphology. VM can change tumor microcirculation, progression, and metastasis. However, the molecular mechanisms of endothelial-like transition remain unclear.