The prevalence of self-neglect among older adults: A systematic review and meta-analysis.

Purpose: To quantitatively pool the overall prevalence of self-neglect in older adults and provide evidence-based information for healthcare professionals to develop preventive measures.

Methods: Systematically and thoroughly searched ten databases from inception to September 1, 2024 and we pooled the prevalence of self-neglect in older adults using a random-effects model based on the Stata 15.0 software.

Trends in osteoporosis assessment, diagnosis after fragility fractures, and treatment for hospitalized patients with osteoporosis or fragility fractures between 2012 and 2021.

Unlabelled: Our study investigated trends in osteoporosis management in Xiamen from 2012 to 2021, revealing improvements in screening and treatment, although medication use remained low. Additionally, we identified factors that may influence medication use and emphasized the importance of effective osteoporosis management strategies.

Purpose: The goal of the current study is to explore trends in assessment, diagnosis after fragility fractures, and osteoporosis treatment among hospitalized patients in Xiamen, China, between 2012 and 2021.

Avermectins and Their Derivatives: Recent Advances in Biosynthesis and Application.

Avermectins (AVMs) and their derivatives are the most effective and widely used nematicides, insecticides, and acaricides against endo- and ectoparasites of plants, animals, and humans. Demand for avermectins and their highly effective derivatives has increased due to their high cost-effectiveness and wide range of applications as medicines and crop protection products. Due to the unique structures of these compounds and for industrial production purposes, numerous efforts and strategies have been dedicated to enhancing the production of avermectins and creating new analogues in recent years.

CoO with the Enhancement of Peroxymonosulfate Adsorption Capacity by Rare Earth Europium-Doping for High-Efficiency Organic Dye Degradation.

Cobalt-based metal-organic framework (MOFs)-derived catalysts are acknowledged for their effectiveness in activating peroxymonosulfate (PMS) for the treatment of persistent pollutants. However, the limited adsorption of PMS on the catalyst surface markedly reduces its degradation efficiency. To overcome this limitation, nanoflower-like EuO/CoO-0.

Exploration and validation of a novel reactive oxygen species-related signature for predicting the prognosis and chemotherapy response of patients with bladder cancer.

Background: Reactive Oxygen Species (ROS), a hallmark of cancer, is related to prognosis, tumor progression, and treatment response. Nevertheless, the correlation of ROS-based molecular signature with clinical outcome and immune cell infiltration has not been thoroughly studied in bladder cancer (BLCA). Accordingly, we aimed to thoroughly examine the role and prognostic value of ROS-related genes in BLCA.

Exposure to PM and its components leads to obesity: role of socioeconomic status.

Exposure to air pollutants is linked to an increased risk of obesity, and socioeconomic status (SES) could modulate this risk. We employed the "Jinchang Cohort" as a platform to investigate the influence of SES (education level, monthly income per household, and marital status) on the obesity risk associated with PM and its constituents. Study has demonstrated that air pollutant exposure enhances the likelihood of overweight/obesity, with a risk ratio (HR) of 1.

Long-term survival of a kidney transplant patient with advanced renal cancer after combination therapy: a case report and literature review.

renal transplant carcinoma, especially in the context of bilateral renal carcinoma, is rare and often presents as small, low-grade papillary renal cell carcinoma (RCC). There is currently no consensus or effective treatment for advanced metastatic RCC after kidney transplantation. A 40-year-old man developed renal transplant carcinoma with venous thrombus and lung metastases 13 years after transplantation.

Construction and microencapsulation of tea polyphenols W/O/W double emulsion based on modified gluten (MEG).

The objective of this study was to solve instability and low bioavailability of tea polyphenols (TPs), and to explore the application of gluten protein as microcapsule wall material. Modified gluten protein (MEG), β-cyclodextrin (β-CD), xanthan gum (XG) or acacia gum (GA) were used as composite wall materials to encapsulate TPs by double-emulsion technique, and the physicochemical and structural properties of the products were characterized. The results show that the composite wall material effectively encapsulated and enhanced the stability of TPs.

Development and Comprehensive Evaluation of Culture-Independent, Long Amplicon-Based Targeted Next-Generation Sequencing Methods for Predicting Antimicrobial Resistance in Tuberculosis.

The great variety of antimicrobial resistance (AMR) profiles among tuberculosis (TB) patients necessitates a comprehensive detection method. This study developed culture-independent, long amplicon-based targeted next-generation sequencing (tNGS) methods for predicting AMR across 16 drugs within the complex (MTBC). Multiplex PCR amplification was employed to enrich 20 gene regions, with sequencing performed on either the Oxford Nanopore Technologies (ONT) or Illumina platforms.

Balancing methane emission and alkalinity conservation: Insights from mineral amendments in coastal sediments.

With global climate warming and ocean acidification, mineral amendments in coastal areas have emerged as a promising strategy to bolster carbon sinks and alkalinity. However, most research has predominantly focused on carbon dioxide (CO) absorption, with limited exploration of methane (CH) reduction despite its more potent greenhouse effect. To address this gap, our study conducted a microcosm manipulative experiment employing coastal wetlands sediments to elucidate the regulatory effects of various mineral amendments on greenhouse gas emissions (including CO and CH) and seawater alkalinity.

Ferrocene-decorated graphene nanosheets built by edge-to-face π-π interaction for room temperature ppb-level NO sensing.

The development of materials toward ppb-level nitric oxide (NO) sensing at room temperature remains in high demand for the monitoring of respiratory inflammatory diseases. In order to find an iron-containing molecule without steric hindrance to combine with graphene for room temperature NO gas sensing, here a supramolecular assembly of ferrocene (Fc) and reduced graphene oxide (rGO) was designed and prepared for NO sensing. The assembly of Fc/rGO was characterized using FT-IR, TEM, and XPS measurements.

Anti-FDX1 Autoantibody as a Potential Biomarker for Non-Small Cell Lung Cancer Detection.

Background: Autoantibodies can be readily identified prior to biopsy and may serve as valuable biomarkers for cancer detection. Ferredoxin 1 (FDX1) is a key regulator in the process of cuproptosis and affects the prognosis of lung cancer. In this study, we investigated whether the anti-FDX1 autoantibody could serve as a novel biomarker for the detection of non-small cell lung cancer (NSCLC).

WRKY1-Mediated Interconversion of MeSA and SA in Neighbouring Apple Plants Enhances Defence Against Powdery Mildew.

Powdery mildew (PM), caused by the biotrophic fungus Podospharea leucotricha, is a major threat to apple production. Plant-plant communication (PPC) is a crucial strategy for plant communities to enhance their defence against pathogens. The interconversion of methyl salicylate (MeSA) and salicylic acid (SA) is critical for PPC regulation, but the mechanism of MeSA-mediated PPC is not fully understood.

METTL4-Mediated Mitochondrial DNA N6-Methyldeoxyadenosine Promoting Macrophage Inflammation and Atherosclerosis.

Background: Mitochondrial dysfunction is a key factor in the development of atherogenesis. METTL4 (methyltransferase-like protein 4) mediates N6- methyldeoxyadenosine (6mA) of mammalian mitochondrial DNA (mtDNA). However, the role of METTL4-mediated mitoepigenetic regulation in atherosclerosis is still unknown.

A Retrospective Data Audit of Outcome of Moderate and Severe Covid-19 Patients Who Had Received MP and Dex: A Single Center Study.

Purpose: To evaluate the necessity of the application of glucocorticoid (GC) in moderate COVID-19 patients, and which is the optimal choice between methylprednisolone (MP) and dexamethasone (DEX) in the clinical use of GC in different types of COVID-19 patients.

Patients And Methods: The study included patients with COVID-19 in Shanxi, China, from December 18, 2022, to March 1, 2023. The main clinical outcomes were 30-day mortality, disease exacerbations, and hospitalization days.

Constructing ecological security patterns using remote sensing ecological index and circuit theory: A case study of the Changchun-Jilin-Tumen region.

Rapid urbanization and the implementation of ecological civilization initiatives are increasingly influencing regional ecosystems, necessitating a balance between urban development and ecological conservation for sustainable progress. The Changchun-Jilin-Tumen (CJT) region, a critical grain production base and ecological security barrier in China, faces the challenge of managing urban growth, food security, and ecological stability. This study proposes an integrated approach combining the Remote Sensing Ecological Index (RSEI) and circuit theory to develop an Ecological Security Pattern (ESP) for the region.

Pro-197-Ser mutation combinations in acetolactate synthase (ALS) homoeologous genes affect ALS inhibitor herbicide resistance levels in Monochoria korsakowii.

Background: Monochoria korsakowii is a common broadleaf weed found in rice (Oryza sativa) fields. Acetolactate synthase (ALS) inhibitor herbicides are commonly used to control broadleaf weeds in rice fields. However, prolonged herbicide use has exacerbated resistance issues.

Physical and mental health status and influencing factors of older adults in community-dwelling in Northeast China: a cross-sectional study.

Background: Between 2020 and 2022, the COVID-19 pandemic spread globally, and the implementation of preventive measures led to reduced outdoor activities for older adults, resulting in a decline in social functioning. This study aims to improve community-based health interventions tailored to older adults experiencing physical and psychological declines following the COVID-19 pandemic.

Methods: This study utilized previous data mining results to estimate the demand for community health services for older adults.

State-to-State Time-Dependent Quantum Dynamics Studies of the Si(P) + OH(X Π) → OSi(X Σ) + H(S) Reaction Based on a New HOSi(XA') Potential Energy Surface.

Quantum and quasi-classical dynamics calculations were conducted for the reaction of Si with OH on the latest potential energy surface (PES), which is obtained by fitting tens of thousands of energy points by using the many-body expansion formula. To obtain an accurate PES, all energy points calculated with aug-cc-pVQZ and aug-cc-pV5Z basis sets were extrapolated to the complete basis set limit. The accuracy of our new PES was verified by comparing the topographic characteristics and contour maps of potential energy with other works.

Intravenous thrombolysis and risk of early-onset post-stroke depression: a propensity score matched cohort study.

Background: Depression is common in stroke survivors and affects their recovery and quality of life (QoL). Intravenous thrombolysis (IVT) can improve post-stroke outcomes but the impact on early-onset post-stroke depression (PSD) is unclear. This was evaluated by comparing depression symptoms between patients with acute ischemic stroke (AIS) with vs.

A New Strategy for Enhancing Postharvest Quality of Sweet Cherry: High-Voltage Electrostatic Field Improves the Physicochemical Properties and Fungal Community.

Sweet cherry has a short shelf life due to the occurrence of senescence and fungal infection after harvest. This study aimed to study the effects of high-voltage electrostatic field (HVEF) on the physicochemical properties and fungal composition of sweet cherry during cold storage. The experiments were conducted at 4 °C for 28 days and the quality indicators were determined every 7 days during the period of storage.

Reproductive Tract Mucus May Influence the Sex of Offspring in Cattle: Study in Cows That Have Repeatedly Calved Single-Sex Offspring.

This study aimed to investigate the selective effect of the reproductive tract mucus in cows that have consistently produced offspring of a single sex on X/Y spermatozoa. We collected mucus from the reproductive tract of cows that had given calvings to offspring of the same sex, or alternated between sexes, for more than five consecutive calvings. We evaluated the pH of reproductive tract mucus.