Endocannabinoid system in the neurodevelopment of GABAergic interneurons: implications for neurological and psychiatric disorders.

In mature mammalian brains, the endocannabinoid system (ECS) plays an important role in the regulation of synaptic plasticity and the functioning of neural networks. Besides, the ECS also contributes to the neurodevelopment of the central nervous system. Due to the increase in the medical and recreational use of cannabis, it is inevitable and essential to elaborate the roles of the ECS on neurodevelopment.

Silica-Organometallic One-Dimensional Hybrid Employing a Ag-π Bond Connecting Alternating Ag(NO) and Octavinylsilsesquioxane.

Layering AgNO in alcohol onto octavinylsilsesquioxane (OVS) in CHCl results in a one-dimensional coordination polymer, {Ag(NO)(OVS)·solvents} (), consisting of unprecedented flat weakly bonded Ag(NO) alternating with the firmly covalent OVS through Ag-π bonds. The preferential assembling medium for is proven to be alcohols, where a 4:1 silver-OVS adduct is detected by electrospray ionization mass spectrometry. The present outcomes may assist our knowledge of particular interactions for supramolecular architectures of a polynuclear silver system built from OVS containing eight pendent olefin tails.