Publications by authors named "Lu-Ye Shi"
Article Synopsis
- Long-lived mammals, including certain bat species, are thought to show greater resistance to cancer, but this idea has not been thoroughly studied until now.
- A research study focused on seven bat species, finding that Myotis pilosus (MPI) exhibits particularly strong resistance to cancer when oncogenic genes are activated in their cells.
- The study identified that downregulating three specific genes (HIF1A, COPS5, and RPS3) is key to MPI's cancer resistance, revealing important insights into the biological mechanisms that help some mammals avoid cancer.
Article Synopsis
- Oxygen is vital for life, and a lack of it (hypoxia) can lead to severe health issues, but some species, like Qinghai and Brandt's voles, have adapted to thrive in low-oxygen environments.
- The study compared the physiological and molecular responses of these voles under hypoxic and normoxic conditions, finding they tolerate low oxygen much better than Kunming mice, which suffered significant cardiac damage.
- The voles employ different strategies to cope with hypoxia, with Qinghai voles enhancing heart function and oxygen transport, while Brandt's voles focus on increasing red blood cell production, illustrating their unique adaptations to oxygen scarcity.
Many phylogeographic studies on marine organisms in the Northwestern Pacific have supported for the biogeographic hypotheses that isolation in the marginal seas of this region during the Pleistocene glaciation lower sea level led to population genetic divergence, and thus population expansion was a common phenomenon when the sea level rebounded. However, most of these studies were based on maternally inherited mitochondrial DNA markers with limited sample sites and therefore, were unable to reveal detailed pictures encompassing paternal line information covering of the entire range. In this study, we used the mitochondrial cytochrome c oxidase subunit I (COI) and nine nuclear microsatellite loci to investigate the phylogeography of the mud snail, (Philippi, 1849), a species endemic to the Northwestern Pacific.
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